Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21276153 | 1.00 | MGLL (0.65) | MGLLFAAH | |
| SCHEMBL21276341 | 1.00 | MGLL (0.65) | MGLLFAAH | |
| SCHEMBL21276347 | 0.94 | MGLL (0.58) | MGLLFAAH | |
| SCHEMBL21257974 | 0.93 | FAAH (0.62) | MGLLFAAH | |
| SCHEMBL21276309 | 0.92 | MGLL (0.65) | MGLLFAAH | |
| SCHEMBL21276168 | 0.91 | MGLL (0.64) | MGLLFAAH | |
| SCHEMBL21276290 | 0.90 | MGLL (0.76) | MGLLFAAH | |
| SCHEMBL21276329 | 0.88 | FAAH (0.68) | MGLLFAAH | |
| SCHEMBL21276287 | 0.87 | MGLL (0.60) | MGLLFAAH | |
| SCHEMBL21276291 | 0.87 | FAAH (0.54) | MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | FAAH, FAAH2, MGLL | MGLL 3/4885FAAH 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.