Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884916 | 1.00 | HDAC7 (0.43) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL4595724 | 0.86 | CA2 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL4594560 | 0.86 | CA2 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL4594802 | 0.86 | CA2 (0.52) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL7477484 | 0.85 | HDAC7 (0.39) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL12285998 | 0.85 | CA1 (0.45) | SLC1A2SLC1A1GRIK1GRIK2CA1 | |
| SCHEMBL25389975 | 0.83 | GRIK1 (0.44) | SLC1A2SLC1A1GRIK1GRIK2CA1 | |
| SCHEMBL28458244 | 0.83 | GRIK1 (0.44) | SLC1A2SLC1A1GRIK1GRIK2CA1 | |
| SCHEMBL28958158 | 0.83 | GRIK1 (0.44) | SLC1A2SLC1A1GRIK1GRIK2CA1 | |
| SCHEMBL15338772 | 0.82 | GRIK1 (0.39) | HDAC7HDAC8HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-10 | — | — | US | disclosed |
| CN-105481862-B | novel inhibitors of F L T3 kinase and uses thereof | 中国科学院合肥物质科学研究院 | 2018-08-21 | — | — | CN | disclosed |
| US-20150152064-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-06-04 | — | — | US | disclosed |
| EP-2215148-B1 | ORGANOPOLYSILOXANES COMPRISING QUATERNARY AMMONIUM GROUPS, THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20100243944-A1 | ORGANOPOLYSILOXANES CONTAINING QUATERNARY AMMONIUM GROUPS, THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2010-09-30 | — | — | US | disclosed |
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |
| US-4246151-A | COMPOSITION COMPRISING THE REACTION PRODUCT OF AN EPOXIDIZED ADDITION POLYMER WITH AN AMINE, PLUS A PARTIALLY OR FULLY BLOCKED POLYISOCYANATE | AKZO N.V. (NL) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | ALOX15, LOX, ALOX12 | HDAC7 1473/4885HDAC8 1854/4885HDAC6 2029/4885 |
| US-20150152064-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | EIF2AK2, NSUN3, NSUN2 | HDAC7 2043/4885HDAC8 1989/4885HDAC6 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.