Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970681 | 0.86 | DNM1 (0.55) | DNM1MMP2MEN1KMT2AEPHX1 | |
| SCHEMBL26838432 | 0.86 | MCL1 (0.48) | MCL1DNM1MMP1MMP2MMP3 | |
| SCHEMBL1827225 | 0.83 | MEN1 (0.54) | DNM1MEN1KMT2ATSHREPHX1 | |
| SCHEMBL8741153 | 0.83 | MEN1 (0.48) | DNM1MEN1KMT2ATSHRCASP2 | |
| SCHEMBL31620138 | 0.83 | CASP2 (0.62) | DNM1MEN1KMT2AEPHX1CASP2 | |
| SCHEMBL29312927 | 0.83 | CASP2 (0.62) | DNM1MEN1KMT2AEPHX1CASP2 | |
| SCHEMBL5353889 | 0.83 | CASP2 (0.62) | DNM1MEN1KMT2AEPHX1CASP2 | |
| SCHEMBL18871729 | 0.83 | CASP2 (0.62) | DNM1MEN1KMT2AEPHX1CASP2 | |
| SCHEMBL18402599 | 0.83 | CASP2 (0.62) | DNM1MEN1KMT2AEPHX1CASP2 | |
| SCHEMBL31620140 | 0.83 | CASP2 (0.62) | DNM1MEN1KMT2AEPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250513-A1 | 13-MEMBERED MACROLIDE COMPOUNDS FOR TREATING DISEASES MEDIATED BY ABNORMAL PROTEIN TRANSLATION | ZIKANI THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| US-9802178-B2 | Carrier for blood component adsorption and blood component adsorption column | TORAY INDUSTRIES, INC. (JP) | 2017-10-31 | — | — | US | disclosed |
| US-8461328-B2 | Tricyclic heterocyclic compounds, compositions and methods of use thereof | GENENTECH, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| WO-2013007768-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF AS JAK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | disclosed |
| WO-2012085176-A1 | TRICYCLIC PYRAZINONE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF AS JANUS KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-28 | — | — | WO | disclosed |
| EP-2215148-B1 | ORGANOPOLYSILOXANES COMPRISING QUATERNARY AMMONIUM GROUPS, THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2011086053-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2011-07-21 | — | — | WO | disclosed |
| US-20100243944-A1 | ORGANOPOLYSILOXANES CONTAINING QUATERNARY AMMONIUM GROUPS, THE PRODUCTION AND USE THEREOF | WACKER CHEMIE AG (DE) | 2010-09-30 | — | — | US | disclosed |
| WO-2010013086-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-02-04 | — | — | WO | disclosed |
| US-20080132500-A1 | Antibiotic compounds | MERCK SHARP & DOHME CORP. | 2008-06-05 | — | — | US | disclosed |
| US-4246151-A | COMPOSITION COMPRISING THE REACTION PRODUCT OF AN EPOXIDIZED ADDITION POLYMER WITH AN AMINE, PLUS A PARTIALLY OR FULLY BLOCKED POLYISOCYANATE | AKZO N.V. (NL) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132500-A1 | Antibiotic compounds | NRDC, MRPL21, PEPD | MCL1 1952/4885DNM1 1231/4885MMP1 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.