SCHEMBL21277435

SCHEMBL21277435

COC1C(O)[C@@H](CO)O[C@H]1N1C=CC(=O)NC1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 8/20 0.40
▸ LGALS8 O00214 2/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ TK2 O00142 2/20 0.36
▸ MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24059174 0.82 PRKCA (0.31) —
SCHEMBL21283066 0.78 TK2 (0.37) CDALGALS8MEN1KMT2ATK2
SCHEMBL14510444 0.78 TK2 (0.37) CDALGALS8MEN1KMT2ATK2
SCHEMBL23353386 0.78 TK2 (0.37) CDALGALS8MEN1KMT2ATK2
SCHEMBL17577520 0.72 MEN1 (0.39) CDALGALS8MEN1KMT2AMAPT
SCHEMBL31685243 0.69 CDA (0.53) CDALGALS8MEN1KMT2AMAPT
SCHEMBL31685726 0.69 MEN1 (0.35) CDALGALS8MEN1KMT2AMAPT
SCHEMBL22886976 0.68 — —
SCHEMBL25053728 0.68 TK2 (0.35) CDATK2
SCHEMBL659076 0.68 LMNA (0.56) TK2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2931319-B1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX INC (US) 2019-08-21 — — EP disclosed
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