SCHEMBL659076

SCHEMBL659076

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(F)c(=O)[nH]c1=O

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
TSHR P16473 1/20 0.56
MAPT P10636 1/20 0.56
PMP22 Q01453 1/20 0.56
HBB P68871 1/20 0.56
PYGM P11217 3/20 0.53
TK2 O00142 6/20 0.52
P2RY6 Q15077 2/20 0.52
P2RY14 Q15391 2/20 0.52
NT5E P21589 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659077 1.00 LMNA (0.56) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL28113579 1.00 LMNA (0.56) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL4192644 0.90 P2RY6 (0.51) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL7137093 0.89 LMNA (0.56) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL22992480 0.87 TK2 (0.67) LMNAPYGMTK2
SCHEMBL62322 0.87 TK2 (0.67) LMNAPYGMTK2
SCHEMBL20875706 0.87 TK2 (0.67) LMNAPYGMTK2
SCHEMBL22992424 0.87 TK2 (0.67) LMNAPYGMTK2
SCHEMBL7182936 0.87 TK2 (0.67) LMNAPYGMTK2
SCHEMBL31685558 0.87 PYGM (0.54) PYGMTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090307805-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V 2009-12-10 US claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
US-20240117337-A1 METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 US disclosed
US-20240076719-A9 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-03-07 US disclosed
US-20230295694-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-09-21 US disclosed
US-11725205-B2 Methods and polynucleotides for amplifying a target polynucleotide OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-15 US disclosed
WO-2023147565-A2 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS Opentrons LabWorks Inc. (US) 2023-08-03 WO disclosed
US-20230046363-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-02-16 US disclosed
CN-1916630-A Method for molecular and nano material based on the electric reading of concrete affair of functionalized electrode, and cmod based device INTEL CORP (US) 2007-02-21 CN disclosed
EP-1015643-B1 METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS AGILENT TECHNOLOGIES INC (US) 2005-09-21 EP disclosed
US-20050079505-A1 Electronically readable microarray with electronic addressing function AGILENT TECHNOLOGIES INC 2005-04-14 US disclosed
US-20050069905-A1 Detection of molecular binding events AGILENT TECHNOLOGIES, INC. 2005-03-31 US disclosed
US-20040248104-A1 Methods and reagents for profiling quantities of nucleic acids AGILENT TECHNOLOGIES, INC. 2004-12-09 US disclosed
US-20030022150-A1 Detecting preferential bioplymers in sample; obtain nutrient broths inoculate with cells, immerse electrodes, code cells, incubate cells with substrate, monitor response, evaluate response AGILENT TECHNOLOGIES, INC. 2003-01-30 US disclosed
US-6218118-B1 MIXTURE OF NATURAL AND MASS-MODIFIED GENERIC OLIGONUCLEOTIDE PRECURSORS; USING MIXTURE AND ENZYMATIC PROCESSES TO ALTER THE LENGTH, AND THUS THE MASS, OF PRECURSORS THAT ARE COMPLEMENTARY TO TARGET NUCLEIC ACID AGILENT TECHNOLOGIES, INC. 2001-04-17 US disclosed
EP-1015643-A2 METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS Hewlett-Packard Company (US) 2000-07-05 EP disclosed
WO-2000003038-A2 METHOD AND REAGENTS FOR ANALYZING THE NUCLEOTIDE SEQUENCE OF NUCLEIC ACIDS HEWLETT-PACKARD COMPANY (US) 2000-01-20 WO disclosed
US-5459243-A Apparatus and processes for the large scale generation and transfer of diazomethane ISIS PHARMACEUTICALS, INC. (US) 1995-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM LMNA 171/4885SMN1; SMN2 611/4885TSHR 3395/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 LMNA 3119/4885SMN1; SMN2 3068/4885TSHR 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.