SCHEMBL21279161

SCHEMBL21279161

Cc1ccc2c3ccc(C)cc3n(-c3cc(C#N)c(-c4cc(C)nc(C)n4)cc3-n3c4cc(C)ccc4c4ccc(C)cc43)c2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 5/20 0.33
GLA P06280 2/20 0.33
GAA P10253 2/20 0.33
HTT P42858 1/20 0.33
GRM2 Q14416 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 2/20 0.30
CASP1 P29466 1/20 0.30
RECQL P46063 1/20 0.30
CASP7 P55210 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MAT2A P31153 1/20 0.30
TSHR P16473 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21279164 0.94 KDM4E (0.36) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL21279156 0.89 SETDB1 (0.32) ALDH1A1RECQLTSHR
SCHEMBL21279113 0.88 KDM4E (0.36) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL21278733 0.86 ALDH1A1 (0.32) ALDH1A1HTTHPGDTSHRSMN1; SMN2
SCHEMBL21278841 0.85 CYP1A2 (0.38) ALDH1A1KDM4EGLAHPGDHSD17B10
SCHEMBL21278863 0.85 TSHR (0.36) MAT2ATSHRSMN1; SMN2
SCHEMBL21279158 0.84 PDE10A (0.33) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL21279186 0.84 KDM4E (0.34) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL21278819 0.84 IRAK4 (0.32)
SCHEMBL22563565 0.84 PKM (0.33) ALDH1A1KDM4EGLAGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3399004-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-08-21 EP disclosed