Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15317023 | 1.00 | TSHR (0.40) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15317025 | 0.83 | ALDH1A1 (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21279646 | 0.83 | ALDH1A1 (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21279624 | 0.82 | LMNA (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL15317028 | 0.82 | LMNA (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3140490 | 0.79 | NPC1 (0.53) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL3138175 | 0.79 | NPC1 (0.53) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL3138170 | 0.79 | NPC1 (0.53) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL3137872 | 0.79 | KDM1A (0.39) | ALDH1A1NAMPTKDR | |
| SCHEMBL15957797 | 0.78 | TSHR (0.39) | TSHRALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |