Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15317025 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRNPSR1HPGDLMNA | |
| SCHEMBL15957797 | 0.87 | TSHR (0.39) | ALDH1A1TSHRNPSR1HPGDLMNA | |
| SCHEMBL21279520 | 0.83 | TSHR (0.40) | ALDH1A1TSHRNPSR1HPGDLMNA | |
| SCHEMBL15317023 | 0.83 | TSHR (0.40) | ALDH1A1TSHRNPSR1HPGDLMNA | |
| SCHEMBL15317028 | 0.83 | LMNA (0.38) | ALDH1A1TSHRNPSR1LMNAMEN1 | |
| SCHEMBL21279624 | 0.83 | LMNA (0.38) | ALDH1A1TSHRNPSR1LMNAMEN1 | |
| SCHEMBL2737894 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRNPSR1HPGDLMNA | |
| SCHEMBL17823476 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHRNPSR1HPGDLMNA | |
| SCHEMBL17834209 | 0.76 | ALDH1A1 (0.37) | ALDH1A1TSHRNPSR1HPGDMEN1 | |
| SCHEMBL15317018 | 0.76 | NPSR1 (0.40) | ALDH1A1TSHRNPSR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |