Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737904 | 1.00 | L3MBTL1 (0.37) | L3MBTL1NPSR1LMNAALDH1A1AADAT | |
| SCHEMBL2737994 | 0.91 | L3MBTL1 (0.36) | L3MBTL1NPSR1LMNAALDH1A1AADAT | |
| SCHEMBL2737978 | 0.91 | UCHL1 (0.38) | L3MBTL1NPSR1LMNAALDH1A1AADAT | |
| SCHEMBL2737903 | 0.88 | ALDH1A1 (0.41) | L3MBTL1NPSR1LMNAALDH1A1AADAT | |
| SCHEMBL21279513 | 0.88 | ALDH1A1 (0.41) | L3MBTL1NPSR1LMNAALDH1A1AADAT | |
| SCHEMBL21279510 | 0.86 | TSHR (0.37) | L3MBTL1NPSR1LMNAALDH1A1MAPT | |
| SCHEMBL2737893 | 0.86 | TSHR (0.37) | L3MBTL1NPSR1LMNAALDH1A1MAPT | |
| SCHEMBL2737977 | 0.86 | PDE8B (0.37) | L3MBTL1NPSR1LMNAALDH1A1AADAT | |
| SCHEMBL2737976 | 0.85 | PDE8B (0.39) | L3MBTL1NPSR1LMNAALDH1A1MAPT | |
| SCHEMBL2737986 | 0.85 | ABCB1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838900-B1 | COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-08-21 | — | — | EP | disclosed |