SCHEMBL2127992

SCHEMBL2127992

O=C(O)c1ccc(C(=O)OCCO)c(CCO)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 2/20 0.41
TDP1 Q9NUW8 2/20 0.38
SLC7A5 Q01650 1/20 0.37
TSHR P16473 3/20 0.36
NPC1 O15118 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
TP53 P04637 2/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GLA P06280 2/20 0.34
HPGD P15428 2/20 0.34
RAB9A P51151 2/20 0.34
HSD17B10 Q99714 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ACE2 Q9BYF1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30681852 0.91 TDP1 (0.42) SERPINE1TDP1SLC7A5TSHRNPC1
SCHEMBL21539576 0.90 SERPINE1 (0.39) SERPINE1TDP1SLC7A5TSHRNPC1
SCHEMBL28346744 0.90 CYP4F2 (0.39) SERPINE1TDP1SLC7A5TSHRTP53
SCHEMBL29248413 0.89 LMNA (0.38) SERPINE1TDP1SLC7A5TSHRKDM4E
SCHEMBL25432942 0.88 ALDH1A1 (0.43) TSHRNPC1TP53CYP3A4MAPK1
SCHEMBL2125242 0.85 TDP1 (0.42) SERPINE1TDP1TSHRTP53CYP3A4
SCHEMBL28189094 0.85 ACE2 (0.37) SERPINE1TSHRNPC1MAPK1ACE2
SCHEMBL705602 0.84 KDM4E (0.42) SERPINE1TDP1SLC7A5TSHRKDM4E
SCHEMBL1073276 0.84 KDM4E (0.47) TDP1TSHRKDM4ETP53MAPK1
SCHEMBL9062685 0.83 NPC1 (0.48) NPC1KDM4EALDH1A1GLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605454-A1 IMPROVED METHOD FOR THE DEPOLYMERISATION OF POLYETHYLENE TEREPHTHALATE Evonik Operations GmbH (DE) 2025-08-27 EP claimed
US-20240294726-A1 Method and Reactor System for Depolymerizing a Terephthalate-Polymer Into Reusable Raw Material IONIQA TECHNOLOGIES B.V. (NL) 2024-09-05 US claimed
EP-4359472-A1 METHOD AND REACTOR SYSTEM FOR DEPOLYMERIZING A TEREPHTHALATE-POLYMER INTO REUSABLE RAW MATERIAL Ioniqa Technologies B.V. (NL) 2024-05-01 EP claimed
EP-4359471-A1 METHOD AND REACTOR SYSTEM FOR DEPOLYMERIZING A TEREPHTHALATEPOLYMER INTO REUSABLE RAW MATERIAL Ioniqa Technologies B.V. (NL) 2024-05-01 EP claimed
WO-2024083322-A1 IMPROVED METHOD FOR THE DEPOLYMERISATION OF POLYETHYLENE TEREPHTHALATE EVONIK OPERATIONS GMBH (DE) 2024-04-25 WO claimed
WO-2022271013-A1 METHOD AND REACTOR SYSTEM FOR DEPOLYMERIZING A TEREPHTHALATE-POLYMER INTO REUSABLE RAW MATERIAL IONIQA TECHNOLOGIES B.V. (NL) 2022-12-29 WO claimed
WO-2022271014-A1 METHOD AND REACTOR SYSTEM FOR DEPOLYMERIZING A TEREPHTHALATEPOLYMER INTO REUSABLE RAW MATERIAL IONIQA TECHNOLOGIES B.V. (NL) 2022-12-29 WO claimed
EP-0436570-B1 IMPROVED PROCESS FOR MANUFACTURE OF POLYETHYLENE TEREPHTHALATE FILM CONTAINING SLIP ADDITIVE DU PONT (US) 1996-01-03 EP claimed
US-4101488-A POLYESTERIMIDE RESIN NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1978-07-18 US claimed
US-4097444-A Process for the dyeing of water-insoluble thermoplastic polymers and polycondensates in the mass HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-27 US claimed
US-12570793-B2 Process for formation of additive-containing polyester OCTAL SAOC FZC (OM) 2026-03-10 US disclosed
EP-4605454-A1 IMPROVED METHOD FOR THE DEPOLYMERISATION OF POLYETHYLENE TEREPHTHALATE Evonik Operations GmbH (DE) 2025-08-27 EP disclosed
US-12264116-B2 Method and system embodiments for converting ethanol to para-xylene and ortho-xylene BATTELLE MEMORIAL INSTITUTE (US) 2025-04-01 US disclosed
US-20250091036-A1 CATALYST AND METHOD EMBODIMENTS FOR MAKING PARA-XYLENE AND ORTHO-XYLENE BATTELLE MEMORIAL INSTITUTE (US) 2025-03-20 US disclosed
US-20240294726-A1 Method and Reactor System for Depolymerizing a Terephthalate-Polymer Into Reusable Raw Material IONIQA TECHNOLOGIES B.V. (NL) 2024-09-05 US disclosed
US-4008048-A Installation for the discontinuous production of polyethylene terephthalate AGFA-GEVAERT N.V. (BE) 1977-02-15 US disclosed
US-4007146-A POLYESTER NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-02-08 US disclosed
US-4005056-A Process for the preparation of polyhydantoins and polyparanic acids BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US disclosed
US-4002667-A FROM DIMETHYL TEREPHTHALATE AND ETHYLENE GLYCOL, BASIC CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1977-01-11 US disclosed
US-4002667-A FROM DIMETHYL TEREPHTHALATE AND ETHYLENE GLYCOL, BASIC CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570793-B2 Process for formation of additive-containing polyester VEGFA, AGL, KDR SERPINE1 1459/4885TDP1 2664/4885SLC7A5 1634/4885
US-20240294726-A1 Method and Reactor System for Depolymerizing a Terephthalate-Polymer Into Reusable Raw Material DLST, HAAO, TKT SERPINE1 4471/4885TDP1 1130/4885SLC7A5 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.