Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18496768 | 0.89 | MAOB (0.51) | MAOBMAOAKMT2AMEN1TDP1 | |
| SCHEMBL17367232 | 0.79 | MAOB (0.54) | MAOBMAOAKMT2AMEN1TDP1 | |
| SCHEMBL18015826 | 0.75 | MAOB (0.57) | MAOBMAOACYP3A4KMT2AMEN1 | |
| SCHEMBL18014705 | 0.69 | MAOB (0.53) | MAOBMAOAKMT2AMEN1TDP1 | |
| SCHEMBL7126578 | 0.68 | MAOB (0.51) | MAOBMAOAKMT2AMEN1TDP1 | |
| SCHEMBL25744529 | 0.68 | MAOB (0.39) | MAOBMAOAKMT2AMEN1RAB9A | |
| SCHEMBL25744520 | 0.68 | MAOB (0.48) | MAOBMAOAKMT2AMEN1TDP1 | |
| SCHEMBL18506195 | 0.68 | MAOA (0.47) | MAOBMAOAKMT2AMEN1RAB9A | |
| SCHEMBL8707447 | 0.67 | MAOB (0.50) | MAOBMAOACYP3A4KMT2AMEN1 | |
| SCHEMBL2208757 | 0.66 | HDAC6 (0.60) | MAOBMAOAKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335253-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |