Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515143 | 0.84 | — | — | |
| SCHEMBL2533327 | 0.83 | — | — | |
| SCHEMBL31299205 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTALOX15HTT | |
| SCHEMBL6965651 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTALOX15HTT | |
| SCHEMBL671223 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTALOX15HTT | |
| SCHEMBL19974223 | 0.76 | KMT2A (0.50) | ALDH1A1MEN1MAPTALOX15HTT | |
| SCHEMBL23374501 | 0.76 | HSD17B10 (0.46) | ALDH1A1MEN1MAPTALOX15HTT | |
| SCHEMBL2404722 | 0.76 | HSD17B10 (0.46) | ALDH1A1MEN1MAPTALOX15HTT | |
| SCHEMBL2536916 | 0.76 | CHRNB2 (0.42) | ALDH1A1MEN1KMT2AHSD17B10CHRNB2 | |
| SCHEMBL12216938 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004702-A | — | — | None | — | — | JP | disclosed |
| EP-2699553-B1 | SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2023-11-08 | — | — | EP | disclosed |
| US-20120245173-A1 | INHIBITION OF ACTIVATED CDC42-ASSOCIATED KINASE 1 | Reaction Biology Corporation (US) | 2012-09-27 | — | — | US | disclosed |
| EP-2442809-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| US-7897796-B2 | Treating the taxane mixture (biomass extract derived from Taxus media cultivars) with an amine attached to a silica matrix, e.g., methylated polyethylenimine bonded silica, and elution | PHYTON HOLDINGS, LLC (US) | 2011-03-01 | — | — | US | disclosed |
| WO-2010148197-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20080076936-A1 | Purification of Taxanes and Taxane Mixtures Using Polyethyleneimine-Bonded Resins | NATURAL PHARMACEUTICALS, INC. | 2008-03-27 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |
| JP-H024702-A | INSECT PEST REPELLENT | SUMITOMO CHEM CO LTD | 1990-01-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245173-A1 | INHIBITION OF ACTIVATED CDC42-ASSOCIATED KINASE 1 | TNK2, CDC42BPA, CDC42BPG | ALDH1A1 4776/4885MEN1 1557/4885MAPT 2007/4885 |
| US-20080076936-A1 | Purification of Taxanes and Taxane Mixtures Using Polyethyleneimine-Bonded Resins | PBRM1, PARP1, POLI | ALDH1A1 2169/4885MEN1 1803/4885MAPT 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.