Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21281415 | 0.90 | CPB2 (0.34) | AURKAPDPK1AURKBPDE10APIK3R1 | |
| SCHEMBL22822830 | 0.89 | GPR119 (0.39) | GPR119AURKAPDPK1AURKBPDE10A | |
| SCHEMBL21285555 | 0.84 | KMT2A (0.35) | GPR119FAAHNPC1RAB9AKMT2A | |
| SCHEMBL21285505 | 0.83 | PDE10A (0.38) | GPR119AURKAPDPK1AURKBPDE10A | |
| SCHEMBL22801933 | 0.82 | RET (0.36) | GPR119AURKAPDPK1AURKBPDE10A | |
| SCHEMBL22822876 | 0.82 | RET (0.36) | GPR119AURKAPDPK1AURKBPDE10A | |
| SCHEMBL22801916 | 0.81 | GPR119 (0.40) | GPR119PDE10A | |
| SCHEMBL22801958 | 0.81 | GPR119 (0.40) | GPR119PDE10A | |
| SCHEMBL21269509 | 0.80 | AURKA (0.34) | AURKAPDPK1AURKBPIK3R1PIK3CA | |
| SCHEMBL21269506 | 0.80 | AURKA (0.34) | AURKAPDPK1AURKBPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527209-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB Biopharma SPRL (BE) | 2019-08-21 | — | — | EP | disclosed |