Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127640 | 0.86 | KMT2A (0.68) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL2127495 | 0.82 | ALDH1A1 (0.77) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL2126105 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL2127343 | 0.77 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL1368453 | 0.69 | DAO (0.47) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL13496402 | 0.69 | KMT2A (0.83) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL13496430 | 0.66 | ALDH1A1 (0.83) | ALDH1A1KDM4EHSD17B10NPSR1LMNA | |
| SCHEMBL12594521 | 0.65 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL12595343 | 0.65 | KDM4E (0.79) | ALDH1A1KDM4EHSD17B10NPSR1HPGD | |
| SCHEMBL13496431 | 0.64 | ALDH1A1 (0.76) | ALDH1A1KDM4EHSD17B10NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185507-B1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-04-25 | — | — | EP | claimed |