Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.77 |
| ▸ | HPGD | P15428 | 13/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.77 |
| ▸ | TSHR | P16473 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127343 | 0.86 | KDM4E (0.71) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL12595343 | 0.83 | KDM4E (0.79) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL2128164 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL12594521 | 0.81 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL3625956 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL2127640 | 0.77 | KMT2A (0.68) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL2126105 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL12595339 | 0.73 | KDM4E (0.73) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL13496443 | 0.73 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL30307339 | 0.72 | KDM4E (0.77) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185507-B1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-04-25 | — | — | EP | claimed |
| US-20100144785-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO) ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER SAS (FR) | 2010-06-10 | — | — | US | claimed |
| EP-2185507-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | Bayer CropScience SA (FR) | 2010-05-19 | — | — | EP | claimed |
| WO-2009016221-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | claimed |
| US-8226966-B2 | Fungicide N-6-membered fused (hetero) aryl-methylene-N-cycloalkyl carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-07-24 | — | — | US | disclosed |
| EP-2185507-B1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20100144785-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO) ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER SAS (FR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144785-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO) ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | CBR3, NRDC, CBR1 | ALDH1A1 2589/4885KDM4E 2338/4885HPGD 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.