Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127495 | 0.86 | ALDH1A1 (0.77) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL2126105 | 0.85 | ALDH1A1 (0.62) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL2127640 | 0.82 | KMT2A (0.68) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL12594516 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL13496424 | 0.82 | OPRK1 (0.69) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL13496420 | 0.80 | KDM4E (0.81) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL12594188 | 0.79 | KDM4E (0.76) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL13496429 | 0.77 | KDM4E (0.78) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL2128164 | 0.77 | ALDH1A1 (0.61) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL2425749 | 0.72 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185507-B1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-04-25 | — | — | EP | claimed |
| EP-2185507-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | Bayer CropScience SA (FR) | 2010-05-19 | — | — | EP | claimed |
| WO-2009016221-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | claimed |
| EP-2185507-B1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-2185507-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | Bayer CropScience SA (FR) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016221-A1 | FUNGICIDE N-6-MEMBERED FUSED (HETERO)ARYL-METHYLENE-N-CYCLOALKYL CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | disclosed |