SCHEMBL21282085

SCHEMBL21282085

NS(=O)(=O)c1ccc(NC(=O)CN(CCN(CC(=O)NCCOCCOCCNC(=S)Nc2ccc(-c3c4ccc(=O)cc-4oc4cc(O)ccc34)c(C(=O)O)c2)CC(=O)Nc2ccc(S(N)(=O)=O)cc2)CC(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 20/20 0.71
▸ CA1 P00915 19/20 0.71
▸ CA2 P00918 19/20 0.71
▸ CA12 O43570 10/20 0.71
▸ CA14 Q9ULX7 4/20 0.68
▸ CA7 P43166 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26083930 0.94 CA9 (0.61) CA9CA1CA2CA12CA14
SCHEMBL19370423 0.93 CA9 (0.72) CA9CA1CA2CA12CA14
SCHEMBL21183298 0.91 CA1 (0.58) CA9CA1CA2CA12CA14
SCHEMBL20843771 0.89 CA1 (0.55) CA9CA1CA2CA12CA14
SCHEMBL19370400 0.88 CA9 (0.68) CA9CA1CA2CA12CA14
SCHEMBL18476496 0.86 CA9 (0.80) CA9CA1CA2CA12CA14
SCHEMBL21183305 0.83 CA9 (0.61) CA9CA1CA2CA12CA14
SCHEMBL21728989 0.83 CA9 (0.73) CA9CA1CA2CA12CA14
SCHEMBL21151146 0.83 CA9 (0.73) CA9CA1CA2CA12CA14
SCHEMBL20843768 0.83 CA1 (0.51) CA9CA1CA2CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779602-B2 Methods of use for CAR T cells ENDOCYTE, INC. (US) 2023-10-10 — — US disclosed
US-20210346431-A1 SEQUENCING METHOD FOR CAR T CELL THERAPY Seattle Children's Hospital (dba Seattle Children's Research Institute) 2021-11-11 — — US disclosed
US-20190255109-A1 METHODS OF USE FOR CAR T CELLS ENDOCYTE, INC. 2019-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11779602-B2 Methods of use for CAR T cells CD47, CD4, CD2 CA9 499/4885CA1 829/4885CA2 2378/4885
US-20190255109-A1 METHODS OF USE FOR CAR T CELLS CD47, CD4, CD2 CA9 499/4885CA1 829/4885CA2 2378/4885
US-20210346431-A1 SEQUENCING METHOD FOR CAR T CELL THERAPY CD47, MCTS1, GZMB CA9 567/4885CA1 2463/4885CA2 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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