Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21283007 | 0.91 | KMT2A (0.42) | KMT2AGHSRKDM4EALDH1A1LMNA | |
| SCHEMBL14429284 | 0.86 | KMT2A (0.43) | KMT2AGHSRKDM4EALDH1A1LMNA | |
| SCHEMBL21283009 | 0.84 | GHSR (0.39) | KMT2AGHSRKDM4EALDH1A1LMNA | |
| SCHEMBL23398110 | 0.81 | KDM4E (0.41) | GHSRKDM4EALDH1A1LMNAFOLH1 | |
| SCHEMBL19854872 | 0.80 | LMNA (0.47) | KMT2AGHSRKDM4EALDH1A1LMNA | |
| SCHEMBL18868661 | 0.78 | LMNA (0.43) | KDM4EALDH1A1LMNACA7CA9 | |
| SCHEMBL11454462 | 0.77 | CA1 (0.56) | KMT2AHTTTACR1CA1CA2 | |
| SCHEMBL21283008 | 0.77 | KDM4E (0.36) | GHSRKDM4EALDH1A1LMNAABCB1 | |
| SCHEMBL18868658 | 0.77 | LMNA (0.44) | GHSRKDM4EALDH1A1LMNAFOLH1 | |
| SCHEMBL8920618 | 0.76 | KMT2A (0.51) | KMT2AHTTTACR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3374028-B1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING INKT CELLS | LA JOLLA INST ALLERGY & IMMUNOLOGY (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2017083830-A1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING INKT CELLS | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2017-05-18 | — | — | WO | disclosed |