Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801944 | 0.89 | MAPT (0.38) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL21285657 | 0.89 | MAPT (0.38) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL21268784 | 0.86 | GPR119 (0.40) | PDE10A | |
| SCHEMBL21268782 | 0.86 | GPR119 (0.40) | PDE10A | |
| SCHEMBL22822764 | 0.86 | PDE10A (0.36) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL22801998 | 0.86 | PDE10A (0.36) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL22801999 | 0.86 | PDE10A (0.36) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL22822718 | 0.79 | PDE10A (0.34) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL21285505 | 0.79 | PDE10A (0.38) | PDE10AAURKAPDPK1AURKBPIK3R1 | |
| SCHEMBL21274050 | 0.77 | PIK3R1 (0.35) | PDE10AAURKAPDPK1AURKBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019158731-A1 | PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-08-22 | — | — | WO | disclosed |