Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289501 | 0.78 | TGFBR1 (0.40) | TGFBR1NTRK1 | |
| SCHEMBL21229247 | 0.76 | NTRK1 (0.36) | TGFBR1NTRK1 | |
| SCHEMBL20015876 | 0.69 | DYRK1A (0.39) | TGFBR1 | |
| SCHEMBL21838100 | 0.62 | NTRK1 (0.47) | TGFBR1NTRK1 | |
| SCHEMBL19304135 | 0.62 | AGBL2 (0.39) | PDE10A | |
| SCHEMBL5872614 | 0.62 | KCNH2 (0.51) | TGFBR1 | |
| SCHEMBL15020748 | 0.60 | TDP1 (0.38) | — | |
| SCHEMBL29766744 | 0.59 | SMPD3 (0.58) | NTRK1 | |
| SCHEMBL16848813 | 0.59 | DYRK1A (0.41) | TGFBR1 | |
| SCHEMBL5147052 | 0.59 | CYP3A4 (0.45) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157879-A1 | HETEROCYCLIC COMPOUND WHICH ACTS AS TRK INHIBITOR | 北京诺诚健华医药科技有限公司 | 2019-08-22 | — | — | WO | disclosed |