Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSK | P41240 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 15/20 | 0.35 |
| ▸ | NPY1R | P25929 | 9/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.35 |
| ▸ | NPY2R | P49146 | 5/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20369486 | 0.82 | KISS1R (0.33) | KISS1R | |
| SCHEMBL20857559 | 0.80 | SRC (0.37) | — | |
| SCHEMBL22930531 | 0.75 | KDM1A (0.35) | — | |
| SCHEMBL22878504 | 0.73 | KISS1R (0.35) | KISS1R | |
| SCHEMBL15315067 | 0.72 | CSK (0.54) | CSK | |
| SCHEMBL20878369 | 0.71 | SRC (0.38) | CSK | |
| SCHEMBL13034920 | 0.69 | GRIA1 (0.44) | — | |
| SCHEMBL10441955 | 0.68 | C3AR1 (0.38) | KISS1R | |
| SCHEMBL15315075 | 0.68 | C3AR1 (0.38) | KISS1R | |
| SCHEMBL15691795 | 0.68 | C3AR1 (0.38) | KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256559-A1 | PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF | AILERON THERAPEUTICS, INC. | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256559-A1 | PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF | TP53, TP53BP1, MDM2 | CSK 978/4885NPY4R 3868/4885NPY1R 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.