Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22878504 | 0.90 | KISS1R (0.35) | KISS1RCACNA1BC3AR1 | |
| SCHEMBL22930531 | 0.89 | KDM1A (0.35) | — | |
| SCHEMBL20857557 | 0.83 | KDM1A (0.39) | — | |
| SCHEMBL21286775 | 0.82 | CSK (0.35) | KISS1R | |
| SCHEMBL10441955 | 0.81 | C3AR1 (0.38) | KISS1RCACNA1BC3AR1 | |
| SCHEMBL15315075 | 0.81 | C3AR1 (0.38) | KISS1RCACNA1BC3AR1 | |
| SCHEMBL15691795 | 0.81 | C3AR1 (0.38) | KISS1RCACNA1BC3AR1 | |
| SCHEMBL25138026 | 0.78 | KDM1A (0.33) | — | |
| SCHEMBL19818159 | 0.77 | SIRT6 (0.40) | KISS1RC3AR1 | |
| SCHEMBL13937744 | 0.76 | ANPEP (0.40) | KISS1RC3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10813884-B2 | WNT compositions and methods for purification | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190225650-A1 | PEPTIDOMIMETIC MACROCYCLES AND USE THEREOF IN REGULATING HIF1ALPHA | AILERON THERAPEUTICS, INC. | 2019-07-25 | — | — | US | disclosed |
| US-20180193264-A1 | WNT COMPOSITIONS AND METHODS FOR PURIFICATION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225650-A1 | PEPTIDOMIMETIC MACROCYCLES AND USE THEREOF IN REGULATING HIF1ALPHA | HIF1A, HIF1AN, EGLN3 | KISS1R 1208/4885CACNA1B 4763/4885C3AR1 367/4885 |
| US-10813884-B2 | WNT compositions and methods for purification | WNT3A, CTNNBL1, WNT1 | KISS1R 4586/4885CACNA1B 3451/4885C3AR1 2359/4885 |
| US-20180193264-A1 | WNT COMPOSITIONS AND METHODS FOR PURIFICATION | WNT3A, CTNNBL1, WNT1 | KISS1R 4586/4885CACNA1B 3451/4885C3AR1 2359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.