Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20857557 | 0.94 | KDM1A (0.39) | KDM1A | |
| SCHEMBL25138026 | 0.90 | KDM1A (0.33) | KDM1A | |
| SCHEMBL20369486 | 0.89 | KISS1R (0.33) | — | |
| SCHEMBL21842544 | 0.85 | KDM1A (0.38) | KDM1A | |
| SCHEMBL22878504 | 0.80 | KISS1R (0.35) | — | |
| SCHEMBL15316693 | 0.78 | KDM1A (0.51) | KDM1A | |
| SCHEMBL21286775 | 0.75 | CSK (0.35) | — | |
| SCHEMBL10441955 | 0.72 | C3AR1 (0.38) | — | |
| SCHEMBL15315075 | 0.72 | C3AR1 (0.38) | — | |
| SCHEMBL15691795 | 0.72 | C3AR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127248-A1 | PEPTIDOMIMETIC MACROCYCLES AND FORMULATIONS THEREOF | AILERON THERAPEUTICS, INC. | 2023-04-27 | — | — | US | disclosed |
| US-10905739-B2 | Peptidomimetic macrocycles and formulations thereof | AILERON THERAPEUTICS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127248-A1 | PEPTIDOMIMETIC MACROCYCLES AND FORMULATIONS THEREOF | MDM2, TP53, TP53BP1 | KDM1A 3908/4885 |
| US-10905739-B2 | Peptidomimetic macrocycles and formulations thereof | MDM2, TP53, TP53BP1 | KDM1A 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.