Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.70 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL6515057 | 1.00 | PNP (0.70) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL1375444 | 1.00 | PNP (0.70) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL29171220 | 1.00 | PNP (0.70) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL6130674 | 0.91 | PNP (0.58) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL4348108 | 0.91 | PNP (0.58) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL23880590 | 0.89 | PNP (0.55) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL17597606 | 0.89 | PNP (0.55) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL2526275 | 0.89 | PNP (0.55) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Guanine SCHEMBL20518478 | 0.89 | PNP (0.55) | PNPATAD2ALDH1A1KDM4EMEN1 | |
| Hypoxanthine SCHEMBL3348064 | 0.84 | ATAD2 (0.63) | PNPATAD2ALDH1A1GDAGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898803-B1 | MOLECULAR/GENETIC ABERRATIONS IN SURGICAL MARGINS OF RESECTED PANCREATIC CANCER REPRESENTS NEOPLASTIC DISEASE THAT CORRELATES WITH DISEASE OUTCOME | WAYNE JOHN CANCER INST (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20070031867-A1 | Molecular/genetic aberrations in surgical margins of resected pancreatic cancer represents neoplastic disease that correlates with disease outcome | JOHN WAYNE CANCER INSTITUTE | 2007-02-08 | — | — | US | disclosed |