Sugi Predict

Sugi Predict / Compounds / Hypoxanthine

Hypoxanthine

Hypoxanthine

SCHEMBL3348064

Cc1c[nH]c(=O)[nH]c1=O.O=c1[nH]cnc2nc[nH]c12

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ATAD2 Q6PL18 1/20 0.63
▸ ALDH1A1 P00352 1/20 0.60
▸ PNP P00491 1/20 0.44
▸ PDPK1 O15530 1/20 0.44
▸ GDA Q9Y2T3 2/20 0.43
▸ ACHE P22303 1/20 0.43
▸ PARP1 P09874 1/20 0.39
▸ GRIA1 P42261 1/20 0.38
▸ GRIA2 P42262 1/20 0.38
▸ GRIA3 P42263 1/20 0.38
▸ GRIA4 P48058 1/20 0.38
▸ XDH P47989 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanine SCHEMBL6515057 0.84 PNP (0.70) ATAD2ALDH1A1PNPGDAGRIA1
Adenine SCHEMBL906215 0.84 PI4KA (0.59) ATAD2ALDH1A1PNPPDPK1GDA
Guanine SCHEMBL1375444 0.84 PNP (0.70) ATAD2ALDH1A1PNPGDAGRIA1
Guanine SCHEMBL29171220 0.84 PNP (0.70) ATAD2ALDH1A1PNPGDAGRIA1
Guanine SCHEMBL2128709 0.84 PNP (0.70) ATAD2ALDH1A1PNPGDAGRIA1
Adenine SCHEMBL4633068 0.84 PI4KA (0.59) ATAD2ALDH1A1PNPPDPK1GDA
Adenine SCHEMBL8860590 0.84 PI4KA (0.59) ATAD2ALDH1A1PNPPDPK1GDA
Xanthine SCHEMBL8171996 0.81 GDA (0.72) ATAD2ALDH1A1PNPPDPK1GDA
Hypoxanthine SCHEMBL22323646 0.80 DPYD (0.63) ATAD2ALDH1A1PNPPDPK1GDA
Hypoxanthine SCHEMBL8161237 0.80 ALDH1A1 (0.63) ATAD2ALDH1A1PNPPDPK1GDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109765360-B CMPF homogeneous enzyme immunoassay kit, preparation method and detection method 杭州博谱医药科技有限公司 2020-01-21 — — CN claimed
CN-118126170-A Antibody screening method for clostridium butyricum cell surface protein 美益添生物医药(武汉)有限公司 2024-06-04 — — CN disclosed
CN-114174331-B Antibodies that bind to human metapneumovirus fusion proteins and uses thereof 佐治亚大学研究基金会有限公司 2024-06-04 — — CN disclosed
CN-110294805-B Diagnostic assays and kits for detecting folate receptor 1 伊缪诺金公司 2023-08-15 — — CN disclosed
US-11676682-B1 Methods for accurate sequence data and modified base position determination INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-13 — — US disclosed
WO-2022188883-A1 FUSION PROTEIN OF TNFR2 AND APRIL BAFF RECEPTOR 上海赛金生物医药有限公司 2022-09-15 — — WO disclosed
CN-114174331-A Antibodies that bind human metapneumovirus fusion proteins and uses thereof 佐治亚大学研究基金会有限公司 2022-03-11 — — CN disclosed
US-10562954-B2 Fusion protein inhibiting TACI-BAFF complex formation and preparation method therefor and use thereof SHANGHAI KANDA BIOTECHNOLOGY CO., LTD. (CN) 2020-02-18 — — US disclosed
CN-109765360-B CMPF homogeneous enzyme immunoassay kit, preparation method and detection method 杭州博谱医药科技有限公司 2020-01-21 — — CN disclosed
US-20180018425-A1 METHODS FOR ACCURATE SEQUENCE DATA AND MODIFIED BASE POSITION DETERMINATION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-01-18 — — US disclosed
US-8673559-B2 — — 2014-03-18 — — US disclosed
US-20130230909-A1 METHODS FOR ACCURATE SEQUENCE DATA AND MODIFIED BASE POSITION DETERMINATION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-09-05 — — US disclosed
US-8486630-B2 Methods for accurate sequence data and modified base position determination INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-07-16 — — US disclosed
US-20120295260-A1 METHODS FOR ACCURATE SEQUENCE DATA AND MODIFIED BASE POSITION DETERMINATION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2012-11-22 — — US disclosed
CN-102759625-A Immunoassay application of curcumenol monoclonal antibodies in traditional Chinese medicines including curcumenol UNIV GUILIN MEDICAL 2012-10-31 — — CN disclosed
EP-2245187-A1 METHODS FOR ACCURATE SEQUENCE DATA AND MODIFIED BASE POSITION DETERMINATION Industrial Technology Research Institute (TW) 2010-11-03 — — EP disclosed
WO-2010051773-A1 METHODS FOR ACCURATE SEQUENCE DATA AND MODIFIED BASE POSITION DETERMINATION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (CN) 2010-05-14 — — WO disclosed
US-20100121582-A1 METHODS FOR ACCURATE SEQUENCE DATA AND MODIFIED BASE POSITION DETERMINATION INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2010-05-13 — — US disclosed
US-20070249545-A1 DIHYDROFOLATE REDUCTASE INHIBITION BY EPIGALLOCATECHIN GALLATE COMPOUNDS UNIVERSIDAD DE MURCIA (ES) 2007-10-25 — — US disclosed
WO-2006021888-A2 DIHYDROFOLATE REDUCTASE INHIBITION BY EPIGALLOCATECHIN GALLATE COMPOUNDS UNIVERSIDAD DE MURCIA (ES) 2006-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10562954-B2 Fusion protein inhibiting TACI-BAFF complex formation and preparation method therefor and use thereof IGSF11, BCL9L, FCGR1A ATAD2 3982/4885ALDH1A1 3853/4885PNP 3694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.