SCHEMBL21287945

SCHEMBL21287945

CC(=O)N(C)c1ccn(C(=O)N2CCC3(CCCN3Cc3ccc(Cl)cc3N3CCCC3)CC2)n1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.71
FAAH O00519 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20503474 0.88 FAAH (0.74) MGLLFAAH
SCHEMBL25488266 0.87 MGLL (0.84) MGLLFAAH
SCHEMBL25488275 0.86 MGLL (0.86) MGLLFAAH
SCHEMBL20503487 0.85 MGLL (0.72) MGLLFAAH
SCHEMBL20567600 0.84 MGLL (0.98) MGLLFAAH
SCHEMBL20503550 0.84 MGLL (0.74) MGLLFAAH
SCHEMBL20566589 0.83 MGLL (1.00) MGLLFAAH
SCHEMBL23015505 0.83 MGLL (0.77) MGLLFAAH
SCHEMBL21271404 0.82 MGLL (0.70) MGLLFAAH
SCHEMBL21271363 0.81 MGLL (0.72) MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190256494-A1 PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2019-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190256494-A1 PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 MGLL 21/4885FAAH 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.