SCHEMBL212890

SCHEMBL212890

O=C(OC(=O)c1ccc(Cl)c2ccccc12)c1ccc(Cl)c2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.63
ATM Q13315 1/20 0.63
CYP1A2 P05177 2/20 0.52
CYP2A6 P11509 2/20 0.52
TSHR P16473 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
CNR1 P21554 4/20 0.42
CNR2 P34972 4/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4960400 0.88 CYP1A2 (0.52) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL5751153 0.85 KMT2A (0.59) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL1505134 0.84 CYP1A2 (0.52) KMT2AATMCYP1A2CYP2A6MAPT
SCHEMBL11423051 0.81 KMT2A (0.42) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL4351479 0.79 KMT2A (0.68) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL31284375 0.79 NR4A1 (0.52) CYP1A2TSHRALDH1A1KDM4EHPGD
SCHEMBL8075359 0.79 KMT2A (0.68) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL4639308 0.78 KMT2A (1.00) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL5676787 0.78 KMT2A (0.66) KMT2AATMCYP1A2CYP2A6TSHR
SCHEMBL9166724 0.78 IDO1 (0.54) KMT2ATSHRMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193020-B2 Polyarylene ether sulfone comprising naphthalic acid anhydride endgroups BASF SE (DE) 2021-12-07 US claimed
EP-3577164-B1 POLYARYLENE ETHER SULFONE COMPRISING NAPHTHALIC ACID ANHYDRIDE ENDGROUPS BASF SE (DE) 2021-06-02 EP claimed
US-20260015438-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-15 US disclosed
US-12297316-B2 Orthodontic articles prepared using a polycarbonate diol, polymerizable compositions, and methods of making the articles SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-13 US disclosed
US-20240270893-A1 ORTHODONTIC ARTICLES PREPARED USING A POLYCARBONATE DIOL, POLYMERIZABLE COMPOSITIONS, AND METHODS OF MAKING THE ARTICLES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-08-15 US disclosed
WO-2024137915-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (US) 2024-06-27 WO disclosed
WO-2024119026-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2024-06-06 WO disclosed
WO-2024081802-A1 WAVELENGTH CONVERSION FILM AND DISPLAY DEVICE INCLUDING THE SAME NITTO DENKO CORPORATION (US) 2024-04-18 WO disclosed
US-11945900-B2 Orthodontic articles prepared using a polycarbonate diol, polymerizable compositions, and methods of making the articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-02 US disclosed
US-20230322966-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-10-12 US disclosed
WO-2023158976-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2023-08-24 WO disclosed
EP-0063387-A1 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1982-10-27 EP disclosed
US-4278747-A Electrophotographic plate comprising a conductive substrate and a photosensitive layer containing an organic photoconductor layer composed of a hydrazone compound MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1981-07-14 US disclosed
EP-0028923-A1 1H-Benz (de) isoquinoline -2 (3H) -acetic acid derivatives, processes for their preparation, pharmaceutical compositions containing same and their use AYERST, MCKENNA AND HARRISON INC. (CA) 1981-05-20 EP disclosed
US-4254109-A INHIBIT LENS ALDOSE REDUCTASE AYERST, MCKENNA & HARRISON INC. (CA) 1981-03-03 US disclosed
US-4254108-A ALDOSE REDUCTASE INHIBITORS AYERST, MCKENNA & HARRISON INC. (CA) 1981-03-03 US disclosed
US-4212813-A OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1980-07-15 US disclosed
US-4172202-A Process for the preparation of 4-amino-1,8-naphthalimides HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-23 US disclosed
US-4081446-A DEHALOGENATION, AMMONIATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed
US-4033986-A Process for the preparation of 4-bromo-1,8-naphthalic acid anhydride AMERICAN HOECHST CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015438-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods HTR3D, EIF3D, MYD88 KMT2A 2400/4885ATM 817/4885CYP1A2 1577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.