SCHEMBL8075359

SCHEMBL8075359

O=C(Cl)c1ccc(Cl)c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.68
ATM Q13315 1/20 0.68
CYP1A2 P05177 3/20 0.56
CYP2A6 P11509 3/20 0.56
CNR1 P21554 4/20 0.44
CNR2 P34972 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALOX15 P16050 1/20 0.43
TSHR P16473 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154872 0.89 ALDH1A1 (0.52) KMT2AATMALDH1A1MAPTKDM4E
SCHEMBL29599305 0.89 ALDH1A1 (0.52) KMT2AATMALDH1A1MAPTKDM4E
SCHEMBL4351479 0.83 KMT2A (0.68) KMT2AATMCYP1A2CYP2A6CNR1
SCHEMBL10555469 0.82 ALDH1A1 (0.46) KMT2AATMALDH1A1MAPTKDM4E
SCHEMBL5676787 0.81 KMT2A (0.66) KMT2AATMCYP1A2CYP2A6CNR1
SCHEMBL4639308 0.81 KMT2A (1.00) KMT2AATMCYP1A2CYP2A6CNR1
SCHEMBL11674310 0.80 KMT2A (0.65) KMT2AATMCYP1A2CYP2A6CNR1
SCHEMBL28027192 0.80 NR4A1 (0.54) KMT2AATMCYP1A2ALDH1A1MAPT
SCHEMBL212890 0.79 KMT2A (0.63) KMT2AATMCYP1A2CYP2A6CNR1
SCHEMBL2153429 0.79 ALDH1A1 (0.52) KMT2AATMCYP1A2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260123280-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2026-04-30 US disclosed
EP-4373243-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2024-05-22 EP disclosed
CN-117529987-A Organic light emitting device 株式会社LG化学 2024-02-06 CN disclosed
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed
US-6013648-A IMMUNOMODULATORS SANOFI (FR) 2000-01-11 US disclosed
WO-1998037052-A1 PREPARATION OF ARYL BROMOARYL KETONES AND CARBOXYLIC DERIVATIVES THEREOF ALBEMARLE CORPORATION (US) 1998-08-27 WO disclosed
US-3948939-A 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids STERLING DRUG INC. (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260123280-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, OPRD1 KMT2A 2143/4885ATM 2392/4885CYP1A2 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.