SCHEMBL2128985

SCHEMBL2128985

O=C(O)c1c(O)cc(Cl)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
TPMT P51580 1/20 0.50
HCAR1 Q9BXC0 1/20 0.48
CYP3A4 P08684 2/20 0.46
AKR1C4 P17516 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
ACHE P22303 1/20 0.46
SPR P35270 3/20 0.46
DPP4 P27487 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5355330 0.88 SPR (0.55) TPMTHCAR1CYP3A4AKR1C4AKR1C3
SCHEMBL11209199 0.84 CYP3A4 (0.64) CA1CA2TPMTHCAR1CYP3A4
SCHEMBL5603948 0.78 CYP3A4 (0.70) CA1CA2CA12CA7CA9
SCHEMBL180437 0.78 CYP3A4 (0.70) CA1CA2CA12CA7CA9
Water SCHEMBL1285656 0.76 CYP3A4 (0.67) CA1CA2CA12CA7CA9
Benzene SCHEMBL28591583 0.76 CYP3A4 (0.67) CA1CA2CA12CA7CA9
SCHEMBL8215504 0.76 CYP3A4 (0.67) CA1CA2CA12CA7CA9
Methane SCHEMBL28043126 0.76 CYP3A4 (0.67) CA1CA2CA12CA7CA9
SCHEMBL1042051 0.76 CA12 (0.67) CA1CA2CA12CA7CA9
SCHEMBL111202 0.76 AKR1C4 (0.54) TPMTHCAR1CYP3A4AKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP claimed
EP-0083971-B1 PHOTOSENSITIVE COMPOSITION KONICA CORPORATION (JP) 1987-04-01 EP claimed
EP-0083971-A2 Photosensitive composition KONICA CORPORATION (JP) 1983-07-20 EP claimed
US-20260116891-A1 Oxazepin Derivative TEIJIN PHARMA LTD (JP) 2026-04-30 US disclosed
EP-4651955-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2025-11-26 EP disclosed
EP-4512811-A1 OXAZEPINE DERIVATIVE Teijin Pharma Limited (JP) 2025-02-26 EP disclosed
WO-2024153947-A1 INHIBITOR COMPOUNDS Neophore Limited (GB) 2024-07-25 WO disclosed
WO-2023204308-A1 OXAZEPINE DERIVATIVE 帝人ファーマ株式会社 2023-10-26 WO disclosed
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-5250393-A Containing diazo resin and alkali metal or ammonium silicate FUJI PHOTO FILM CO., LTD. (JP) 1993-10-05 US disclosed
EP-0522457-A1 Photosensitive composition Mitsubishi Chemical Corporation (JP) 1993-01-13 EP disclosed
EP-0492959-A1 Method for developing presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1992-07-01 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP disclosed
EP-0083971-B1 PHOTOSENSITIVE COMPOSITION KONICA CORPORATION (JP) 1987-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116891-A1 Oxazepin Derivative HCRTR2, HCRTR1, OXTR CA1 765/4885CA2 531/4885CA12 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.