SCHEMBL2129077

SCHEMBL2129077

Cc1cc(-c2ccccc2)ncn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 2/20 0.59
MIF P14174 1/20 0.59
KMO O15229 3/20 0.53
RAB9A P51151 4/20 0.52
NPC1 O15118 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KMT2A Q03164 2/20 0.51
HRH4 Q9H3N8 1/20 0.49
TSHR P16473 1/20 0.47
RECQL P46063 1/20 0.47
LDHA P00338 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
PDGFRB P09619 1/20 0.43
KDR P35968 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30412356 1.00 ASIC3 (0.59) ASIC3MIFKMORAB9ANPC1
SCHEMBL28265036 0.98 ASIC3 (0.57) ASIC3MIFKMORAB9ANPC1
SCHEMBL28334660 0.98 ASIC3 (0.57) ASIC3MIFKMORAB9ANPC1
SCHEMBL27908367 0.98 ASIC3 (0.57) ASIC3MIFKMORAB9ANPC1
SCHEMBL19009227 0.90 MIF (0.48) ASIC3MIFKMORAB9ANPC1
SCHEMBL284286 0.84 ASIC3 (0.71) ASIC3MIFKMORAB9ANPC1
SCHEMBL18850043 0.83 FAAH (0.43) ASIC3MIFRAB9ANPC1SMN1; SMN2
SCHEMBL28218682 0.81 ASIC3 (0.68) ASIC3MIFKMORAB9ANPC1
SCHEMBL29406194 0.81 ASIC3 (0.68) ASIC3MIFKMORAB9ANPC1
SCHEMBL27904874 0.81 ASIC3 (0.68) ASIC3MIFKMORAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250126962-A1 Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-04-17 US disclosed
US-20250063937-A1 Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-02-20 US disclosed
US-12150325-B2 Light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-11-19 US disclosed
US-12100795-B2 Light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-09-24 US disclosed
US-20240164124-A1 Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-05-16 US disclosed
WO-2023230179-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING CANCER CASE WESTERN RESERVE UNIVERSITY (US) 2023-11-30 WO disclosed
US-20230363260-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11812626-B2 Light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-11-07 US disclosed
US-11812626-B2 Light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-11-07 US disclosed
US-11812626-B2 Light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-11-07 US disclosed
US-20090075936-A1 Proteasome inhibitors and methods of using the same CEPHALON, INC. (US) 2009-03-19 US disclosed
US-7468383-B2 Proteasome inhibitors and methods of using the same CEPHALON, INC. (US) 2008-12-23 US disclosed
EP-1956022-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2008-08-13 EP disclosed
WO-2008062044-A1 2-HYDROXY-1,3-DIAMINOPROPANE DERIVATIVES NOVARTIS AG (CH) 2008-05-29 WO disclosed
US-20070225296-A1 Arylalkylamine Compound and Process for Preparing the Same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-09-27 US disclosed
US-20070225296-A1 Arylalkylamine Compound and Process for Preparing the Same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-09-27 US disclosed
US-20070142350-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES SANOFI-AVENTIS (FR) 2007-06-21 US disclosed
US-20070142350-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES SANOFI-AVENTIS (FR) 2007-06-21 US disclosed
US-7214798-B2 Derivatives of piperidinyl-and piperazinyl-alkyl carbamates, preparation methods thereof and application of same in therapeutics SANOFI-AVENTIS (FR) 2007-05-08 US disclosed
US-7214798-B2 Derivatives of piperidinyl-and piperazinyl-alkyl carbamates, preparation methods thereof and application of same in therapeutics SANOFI-AVENTIS (FR) 2007-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12100795-B2 Light-emitting element HPRT1, NR2E3, LAGE3 ASIC3 391/4885MIF 2124/4885KMO 4266/4885
US-20250063937-A1 Light-Emitting Element HPRT1, APRT, LAGE3 ASIC3 280/4885MIF 2202/4885KMO 4151/4885
US-20070225296-A1 Arylalkylamine Compound and Process for Preparing the Same CASR, CNR1, CNR2 ASIC3 252/4885MIF 4768/4885KMO 1222/4885
US-20070142350-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, H1-2 ASIC3 195/4885MIF 4646/4885KMO 4095/4885
US-20090075936-A1 Proteasome inhibitors and methods of using the same PSMB11, PSMB5, PSMB6 ASIC3 4111/4885MIF 3964/4885KMO 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.