SCHEMBL2129126

SCHEMBL2129126

C=CC(=O)OC(C)(CC)CCCC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.47
HPGD P15428 1/20 0.47
THRB P10828 5/20 0.37
ALDH1A1 P00352 5/20 0.34
CYP3A4 P08684 2/20 0.34
THRA P10827 2/20 0.34
ATM Q13315 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
CTSK P43235 1/20 0.33
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3244886 0.95 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL5029215 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL31115194 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL20026462 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28780914 0.93 TSHR (0.50) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL29142954 0.89 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL3248687 0.89 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL22403049 0.88 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL20026470 0.88 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL20026693 0.86 TSHR (0.47) TSHRHPGDTHRBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390535-B1 PROCESS FOR PRODUCTION OF POLYOXYMETHYLENE INJECTION MOULDED OBJECTS SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-05-24 EP claimed
CN-111936579-B Use of ethylene and acrylate copolymers prepared in a tubular reactor for modifying the melt rheology of thermoplastic compositions 爱思开致新株式会社 2023-05-09 CN claimed
US-11555116-B2 Use of a copolymer of ethylene and of acrylate(s) prepared in a tubular reactor for modifying the melt rheology of a thermoplastic composition SK GLOBAL CHEMICAL CO., LTD. (KR) 2023-01-17 US claimed
US-11441012-B2 Use of at least one phenolic compound to stabilise ethylene copolymerisation reactions SK GLOBAL CHEMICAL CO., LTD. (KR) 2022-09-13 US claimed
CN-108350623-B Composite system and method for reinforcing a structure made of reinforced concrete or masonry 派雷斯集团股份公司 2021-07-06 CN claimed
US-20210163739-A1 Use of a Copolymer of Ethylene and of Acrylate(s) Prepared in a Tubular Reactor for Modifying the Melt Rheology of a Thermoplastic Composition SK GEO CENTRIC CO., LTD. (KR) 2021-06-03 US claimed
EP-3775045-A1 USE OF A COPOLYMER OF ETHYLENE AND OF ACRYLATE(S) PREPARED IN A TUBULAR REACTOR FOR MODIFYING THE MELT RHEOLOGY OF A THERMOPLASTIC COMPOSITION SK Global Chemical Co., Ltd. (KR) 2021-02-17 EP claimed
CN-111936579-A Use of ethylene and acrylate copolymers prepared in a tubular reactor for modifying the melt rheology of thermoplastic compositions SK综合化学株式会社 2020-11-13 CN claimed
WO-2019186056-A1 USE OF A COPOLYMER OF ETHYLENE AND OF ACRYLATE(S) PREPARED IN A TUBULAR REACTOR FOR MODIFYING THE MELT RHEOLOGY OF A THERMOPLASTIC COMPOSITION ARKEMA FRANCE (FR) 2019-10-03 WO claimed
EP-3496928-A1 POLYMER COMPOSITION COMPRISING A (METH)ACRYLIC POLYMER SABIC Global Technologies B.V. (NL) 2019-06-19 EP claimed
EP-2238225-B1 ETHYLENE/VINYL ACETATE/UNSATURATED ESTERS TERPOLYMER AS ADDITIVE ENCHANCING THE LOW-TEMPERATURE RESISTANCE OF LIQUID HYDROCARBONS TOTAL MARKETING SERVICES (FR) 2016-12-14 EP claimed
US-8980392-B2 Use of a specific functionalised organosilicon compound as a coupling agent in an isoprene elastomer composition including a reinforcing inorganic filler RHODIA OPERATIONS (FR) 2015-03-17 US claimed
US-20120225233-A1 USE OF A SPECIFIC FUNCTIONALISED ORGANOSILICON COMPOUND AS A COUPLING AGENT IN AN ISOPRENE ELASTOMER COMPOSITION INCLUDING A REINFORCING INORGANIC FILLER RHODIA OPERATIONS (FR) 2012-09-06 US claimed
US-20120102825-A1 ETHYLENE/VINYL ACETATE/UNSATURATED ESTERS TERPOLYMER AS AN ADDITIVE FOR IMPROVING THE RESISTANCE TO COLD OF LIQUID HYDROCARBONS SUCH AS MIDDLE DISTILLATES AND FUELS TOTAL RAFFINAGE MARKETING (FR) 2012-05-03 US claimed
US-20100281762-A1 ETHYLENE/VINYL ACETATE / UNSATURATED ESTERS TERPOLYMER AS ADDITIVES ENHANCING THE LOW-TEMPERATURE RESISTANCE OF LIQUID HYDROCARBONS SUCH AS MIDDLE DISTILLATES AND MOTOR FUELS OR OTHER FUELS TOTAL RAFFINAGE MARKETING (FR) 2010-11-11 US claimed
US-20080181859-A1 Novel block (Co)polymers, compositions containing them, method of treatment and method of preparation L'OREAL S.A. (FR) 2008-07-31 US claimed
US-5442005-A Applying a mixture of acrylic copolymer and lubricant selected from natural and synthetic waxes, graphite and deionized water PROCOAT S.A. (ES) 1995-08-15 US claimed
EP-0317684-B1 MULTI-FUNCTION PROTECTIVE COATING FOR ZINC COATED STEEL - SURFACES AND ITS ALLOYS PROCOAT, S.A. (ES) 1993-06-16 EP claimed
EP-0200589-B1 ADHESIVE LAYER USED IN THE MANUFACTURE OF LAMINATED SAFETY GLASS, AND LAMINATED SAFETY GLASS CONTAINING SUCH A LAYER SAINT-GOBAIN VITRAGE INTERNATIONAL (FR) 1989-12-13 EP claimed
US-3962054-A IRRADIATION CROSSLINKING AGENCE NATIONAL DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1976-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181859-A1 Novel block (Co)polymers, compositions containing them, method of treatment and method of preparation XRCC5, TBCB, ERCC5 TSHR 2349/4885HPGD 2248/4885THRB 831/4885
US-11441012-B2 Use of at least one phenolic compound to stabilise ethylene copolymerisation reactions MYB, ECE1, HPD TSHR 4857/4885HPGD 553/4885THRB 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.