Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.58 |
| ▸ | THRA | P10827 | 16/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044652 | 0.93 | THRB (0.66) | THRBTHRA | |
| SCHEMBL13946979 | 0.88 | THRB (0.59) | THRBTHRA | |
| SCHEMBL21291190 | 0.83 | THRA (0.53) | THRBTHRA | |
| SCHEMBL21565782 | 0.79 | THRB (0.52) | THRBTHRA | |
| SCHEMBL13381930 | 0.77 | THRA (0.64) | THRBTHRA | |
| SCHEMBL21291353 | 0.77 | THRA (0.55) | THRBTHRA | |
| SCHEMBL282588 | 0.74 | THRB (1.00) | THRBTHRA | |
| SCHEMBL3159601 | 0.74 | THRB (0.59) | THRBTHRA | |
| SCHEMBL3147833 | 0.74 | THRA (0.66) | THRBTHRA | |
| SCHEMBL13381608 | 0.74 | THRB (0.85) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190255080-A1 | METHOD OF REDUCING THYROID-ASSOCIATED SIDE EFFECTS | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190255080-A1 | METHOD OF REDUCING THYROID-ASSOCIATED SIDE EFFECTS | TSHR, TPO, THRA | THRB 4/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.