Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 20/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 18/20 | 0.55 |
| ▸ | ALDH1A2 | O94788 | 16/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747379 | 0.84 | ALDH1A1 (0.58) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL939933 | 0.82 | ALDH1A1 (0.64) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL21271734 | 0.79 | ALDH1A1 (0.62) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL19747395 | 0.79 | ALDH1A1 (0.62) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL15865180 | 0.73 | ALDH1A1 (0.60) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL15865177 | 0.73 | ALDH1A1 (0.60) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL19746635 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL19746882 | 0.71 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL30358125 | 0.71 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL19745999 | 0.70 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11944626-B2 | Small molecule inhibitors of ALDH and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-04-02 | — | — | US | disclosed |
| EP-3471712-B1 | SMALL MOLECULE INHIBITORS OF ALDH AND USES THEREOF | UNIV MICHIGAN REGENTS (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20190255055-A1 | SMALL MOLECULE INHIBITORS OF ALDH AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11944626-B2 | Small molecule inhibitors of ALDH and uses thereof | ALDH2, ALDH1A1, ALDH3A1 | ALDH1A1 2/4885ALDH1A3 9/4885ALDH1A2 4/4885 |
| US-20190255055-A1 | SMALL MOLECULE INHIBITORS OF ALDH AND USES THEREOF | ALDH2, ALDH1A1, ALDH3A1 | ALDH1A1 2/4885ALDH1A3 9/4885ALDH1A2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.