Pyridine

Pyridine

SCHEMBL21291902

CCNS(=O)(=O)O.c1ccncc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
NAPRT Q6XQN6 2/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 6/20 0.36
LMNA P02545 5/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
MAPT P10636 1/20 0.31
PLOD2 O00469 1/20 0.31
PLOD3 O60568 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL29135433 0.80 TDP1 (0.43) TDP1NAPRTTSHRALDH1A1LMNA
Pyridine SCHEMBL29129492 0.80 NAPRT (0.47) TDP1NAPRTTSHRALDH1A1LMNA
Pyridine SCHEMBL29129469 0.80 NAPRT (0.47) TDP1NAPRTTSHRALDH1A1LMNA
Pyridine SCHEMBL3102492 0.80 NAPRT (0.47) TDP1NAPRTTSHRALDH1A1LMNA
Pyridine SCHEMBL546119 0.79 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1LMNA
Benzene SCHEMBL27460903 0.79 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1LMNA
Pyridine SCHEMBL10678990 0.79 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1LMNA
Pyridine SCHEMBL28192777 0.79 NAPRT (0.53) TDP1NAPRTTSHRALDH1A1LMNA
SCHEMBL177824 0.79
Pyridine SCHEMBL8371169 0.77 NAPRT (0.50) TDP1NAPRTTSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109803952-B Sulfamic acid derivatives and process for preparing same 魁北克电力公司 2022-10-04 CN disclosed
US-11345657-B2 Sulfamic acid derivatives and processes for their preparation HYDRO-QUEBEC (CA) 2022-05-31 US disclosed
EP-3529232-A1 SULPHAMIC ACID DERIVATIVES AND PRODUCTION METHODS THEREOF Hydro-Québec (CA) 2019-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345657-B2 Sulfamic acid derivatives and processes for their preparation STS, SCLY, MPST TDP1 4092/4885NAPRT 566/4885TSHR 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.