Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | CA4 | P22748 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA3 | P07451 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 5/20 | 0.58 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28144641 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL131695 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL28395178 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL18045508 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL20139217 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL4249298 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL3974837 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL20264 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL28873525 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 | |
| Phenol SCHEMBL28109432 | 0.97 | CA2 (0.69) | CA2CA4CA12CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594965-A | Polyphenylene ether resin composition | 旭化成株式会社（JP） | 2023-01-13 | — | — | CN | disclosed |
| US-20190309162-A1 | POLYPHENYLENE ETHER RESIN COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-10-10 | — | — | US | disclosed |
| EP-3530697-A1 | POLY(PHENYLENE ETHER) RESIN COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-08-28 | — | — | EP | disclosed |