Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19876078 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1ATMTDP1LMNA | |
| SCHEMBL288246 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL22992380 | 0.77 | ALDH1A1 (0.43) | LPAR1LPAR3ALDH1A1LMNAPOLB | |
| SCHEMBL28156462 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1ATMTDP1LMNA | |
| SCHEMBL1469633 | 0.74 | LMNA (0.56) | SMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL1470149 | 0.72 | LMNA (0.51) | ALDH1A1LMNAPOLB | |
| SCHEMBL23414150 | 0.71 | RECQL (0.36) | SMN1; SMN2LPAR1ALDH1A1ATM | |
| SCHEMBL37837 | 0.70 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1ATMTDP1LMNA | |
| SCHEMBL28337546 | 0.70 | LMNA (0.55) | SMN1; SMN2ALDH1A1TDP1LMNAPOLB | |
| SCHEMBL1470144 | 0.69 | LMNA (0.50) | ALDH1A1TDP1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3529254-A1 | PRODRUGS OF CLOFARABINE | Wu, Laurence I. (TW) | 2019-08-28 | — | — | EP | disclosed |