SCHEMBL288246

SCHEMBL288246

CCCCCOC(=O)OCC1CO1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.50
NAAA Q02083 1/20 0.43
TSHR P16473 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
EPHX1 P07099 1/20 0.41
ENPP2 Q13822 1/20 0.40
LPAR2 Q9HBW0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19876078 0.95 SMN1; SMN2 (0.56) ALDH1A1TDP1SMN1; SMN2TSHRTP53
SCHEMBL28156462 0.87 SMN1; SMN2 (0.49) ALDH1A1TDP1SMN1; SMN2TSHRTP53
SCHEMBL28337546 0.83 LMNA (0.55) ALDH1A1TDP1SMN1; SMN2TSHR
SCHEMBL1470144 0.82 LMNA (0.50) ALDH1A1TDP1
SCHEMBL377540 0.81 ALDH1A1 (0.57) ALDH1A1TSHRTP53CYP3A4
SCHEMBL1470149 0.80 LMNA (0.51) ALDH1A1
SCHEMBL7574666 0.80 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2TP53CYP3A4
SCHEMBL37366 0.79 NAAA (0.62) ALDH1A1NAAATSHRTP53CYP3A4
SCHEMBL21291971 0.79 SMN1; SMN2 (0.39) ALDH1A1TDP1SMN1; SMN2
SCHEMBL26906538 0.79 TSHR (0.58) ALDH1A1TDP1SMN1; SMN2TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130295381-A1 LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY TRILLION SCIENCE, INC. 2013-11-07 US claimed
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2012-02-02 US claimed
US-20120007259-A1 LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY TRILLION SCIENCE, INC. (US) 2012-01-12 US claimed
US-8084553-B2 Curable adhesive compositions, process, and applications TRILLION SCIENCE, INC. (US) 2011-12-27 US claimed
US-8044154-B2 Latent hardener for epoxy compositions TRILLION SCIENCE, INC. (US) 2011-10-25 US claimed
US-20110220401-A1 LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY TRILLION SCIENCE, INC. (US) 2011-09-15 US claimed
JP-2011509340-A 2011-03-24 JP claimed
US-20100317545-A1 LATENT HARDENER FOR EPOXY COMPOSITIONS POLAROID B.V. (NL) 2010-12-16 US claimed
WO-2010144236-A1 LATENT HARDENER FOR EPOXY COMPOSITIONS TRILLION SCIENCE, INC. (US) 2010-12-16 WO claimed
WO-2009089314-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2009-07-16 WO claimed
US-20090181165-A1 Curable adhesive compositions, Process, and applications TRILLION SCIENCE, INC. (US) 2009-07-16 US claimed
US-10370557-B2 D1563 radiation curable secondary coating for optical fibers DSM IP ASSETS B.V. (NL) 2019-08-06 US disclosed
US-20170355874-A1 D1563 RADIATION CURABLE SECONDARY COATING FOR OPTICAL FIBERS COVESTRO (NETHERLANDS) B.V. (NL) 2017-12-14 US disclosed
WO-2016080829-A1 D1563 RADIATION CURABLE SECONDARY COATING FOR OPTICAL FIBERS DSM IP ASSETS B.V. (NL) 2016-05-26 WO disclosed
US-20130295381-A1 LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY TRILLION SCIENCE, INC. 2013-11-07 US disclosed
US-20110220401-A1 LATENT HARDENER WITH IMPROVED BARRIER PROPERTIES AND COMPATIBILITY TRILLION SCIENCE, INC. (US) 2011-09-15 US disclosed
US-20100317545-A1 LATENT HARDENER FOR EPOXY COMPOSITIONS POLAROID B.V. (NL) 2010-12-16 US disclosed
WO-2010144236-A1 LATENT HARDENER FOR EPOXY COMPOSITIONS TRILLION SCIENCE, INC. (US) 2010-12-16 WO disclosed
WO-2009089314-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS TRILLION SCIENCE, INC. (US) 2009-07-16 WO disclosed
US-20090181165-A1 Curable adhesive compositions, Process, and applications TRILLION SCIENCE, INC. (US) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029116-A1 CURABLE ADHESIVE COMPOSITIONS, PROCESS, AND APPLICATIONS RBX1, SUZ12, CDH1 ALDH1A1 429/4885TDP1 620/4885SMN1; SMN2 1884/4885
US-20090181165-A1 Curable adhesive compositions, Process, and applications RBX1, SUZ12, CDH1 ALDH1A1 429/4885TDP1 620/4885SMN1; SMN2 1884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.