Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578189 | 0.96 | BCHE (0.50) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL21293888 | 0.92 | BCHE (0.47) | BCHEACHE | |
| SCHEMBL1730116 | 0.81 | — | — | |
| SCHEMBL9935830 | 0.74 | BCHE (0.35) | BCHEACHEKMT2A | |
| SCHEMBL9764886 | 0.73 | KDM4E (0.36) | BCHEACHEMAPT | |
| SCHEMBL6115213 | 0.72 | BCHE (0.69) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL168106 | 0.72 | BCHE (0.38) | BCHEACHEMEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8770190 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9815893 | 0.72 | BCHE (0.88) | BCHEACHEMEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL365128 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190263838-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | COVESTRO DEUTSCHLAND AG (DE) | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263838-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | CYP3A4, CYP3A43, CYP4B1 | ACHE 534/4885BCHE 165/4885MEN1 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.