SCHEMBL21293904

SCHEMBL21293904

CCCCCCCCCCCCB1OC(C)(C)C(C)(C)O1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 5/20 0.42
LIPG Q9Y5X9 5/20 0.42
TSHR P16473 3/20 0.38
THRB P10828 1/20 0.38
DNM1 Q05193 5/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15928015 1.00 LPL (0.42) LPLLIPGTSHRTHRBDNM1
SCHEMBL20139091 1.00 LPL (0.42) LPLLIPGTSHRTHRBDNM1
SCHEMBL20535700 1.00 LPL (0.42) LPLLIPGTSHRTHRBDNM1
SCHEMBL15927978 1.00 LPL (0.42) LPLLIPGTSHRTHRBDNM1
SCHEMBL15923410 1.00 LPL (0.42) LPLLIPGTSHRTHRBDNM1
SCHEMBL6938183 1.00 LPL (0.42) LPLLIPGTSHRTHRBDNM1
SCHEMBL18387576 0.90 LPL (0.37) LPLLIPGTSHRLMNA
SCHEMBL23969676 0.90 ANPEP (0.31) LPLLIPG
SCHEMBL20535258 0.88 FAAH (0.44) LMNAMEN1KMT2AHSD17B10
SCHEMBL20535262 0.88 FAAH (0.44) LMNAMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043636-B2 Method for producing triarylorganoborates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-07-23 US disclosed
US-20240002409-A1 METHOD FOR PRODUCING TRIARYLORGANOBORATES COVESTRO DEUTSCHLAND AG (DE) 2024-01-04 US disclosed
US-11760765-B2 Method for producing triarylorganoborates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2023-09-19 US disclosed
CN-110325521-B Process for preparing triarylorganoborates 科思创德国股份有限公司 2023-08-22 CN disclosed
CN-110177797-B Method for producing triaryl organic borate salts 科思创德国股份有限公司 2022-09-23 CN disclosed
CN-109679045-B Novel green reinforcing resin for tire rubber and composition thereof 山东圣泉新材料股份有限公司 2022-04-12 CN disclosed
US-20220002321-A1 METHOD FOR PRODUCING TRIARYLORGANOBORATES COVESTRO DEUTSCHLAND AG (DE) 2022-01-06 US disclosed
US-11078218-B2 Process for the production of triaryl organoborates COVESTRO DEUTSCHLAND AG (DE) 2021-08-03 US disclosed
EP-3583092-B1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2021-05-26 EP disclosed
US-20190276479-A1 PROCESS FOR THE PRODUCTION OF TRIARYL ORGANOBORATES COVESTRO DEUTSCHLAND AG (DE) 2019-09-12 US disclosed
US-20190263838-A1 METHOD FOR PRODUCING TRIARYLORGANOBORATES COVESTRO DEUTSCHLAND AG (DE) 2019-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002409-A1 METHOD FOR PRODUCING TRIARYLORGANOBORATES KMO, COASY, CYP3A4 LPL 1072/4885LIPG 592/4885TSHR 3184/4885
US-11078218-B2 Process for the production of triaryl organoborates OR10J3, CYP4F3, CYP4B1 LPL 4604/4885LIPG 4125/4885TSHR 2354/4885
US-12043636-B2 Method for producing triarylorganoborates KMO, COASY, CYP3A4 LPL 1072/4885LIPG 592/4885TSHR 3184/4885
US-20190263838-A1 METHOD FOR PRODUCING TRIARYLORGANOBORATES CYP3A4, CYP3A43, CYP4B1 LPL 652/4885LIPG 452/4885TSHR 3341/4885
US-20220002321-A1 METHOD FOR PRODUCING TRIARYLORGANOBORATES CYP3A4, CYP3A43, CYP4B1 LPL 652/4885LIPG 452/4885TSHR 3341/4885
US-11760765-B2 Method for producing triarylorganoborates CYP3A4, CYP3A43, CYP4B1 LPL 652/4885LIPG 452/4885TSHR 3341/4885
US-20190276479-A1 PROCESS FOR THE PRODUCTION OF TRIARYL ORGANOBORATES CYP1B1, CYP3A4, CYP4B1 LPL 3036/4885LIPG 2339/4885TSHR 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.