SCHEMBL21294073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21294074	1.00	TRPV1 (0.41)	TRPV1ESR1ADRA2AADORA3TACR2
	SCHEMBL5326614	0.84	ESR1 (0.50)	TRPV1ESR1ADRA2AADORA3TACR2
	SCHEMBL3701730	0.82	FOLH1 (0.51)	TRPV1ESR1ADRA2AADORA3TACR2
	SCHEMBL16213138	0.82	HSD17B3 (0.46)	TRPV1ESR1ADRA2AADORA3TACR2
	SCHEMBL14675140	0.81	HSD17B3 (0.44)	TRPV1ESR1ADRA2AADORA3TACR2
	SCHEMBL604071	0.78	FOLH1 (0.53)	ESR1SLC7A5
	SCHEMBL14906484	0.78	TRPV1 (0.50)	TRPV1ESR1ADRA2AADORA3TACR2
	SCHEMBL31660799	0.76	CNR1 (0.53)	TRPV1KDM4EALDH1A1LMNATP53
	SCHEMBL10709708	0.76	ITGB3 (0.48)	ESR1ALDH1A1LMNACYP3A4SLC7A5
	SCHEMBL10709699	0.76	ITGB3 (0.48)	ESR1ALDH1A1LMNACYP3A4SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.