Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | CCR4 | P51679 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251145 | 0.82 | CA12 (0.46) | BCHELIPESCN9A | |
| SCHEMBL21294546 | 0.82 | CA12 (0.46) | BCHELIPESCN9A | |
| SCHEMBL21294422 | 0.79 | MAPT (0.39) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26195713 | 0.75 | TSHR (0.38) | ALDH1A1MAPK1SMN1; SMN2PLAUCYP3A4 | |
| SCHEMBL16585292 | 0.74 | NPC1 (0.42) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18839618 | 0.74 | ACACB (0.39) | HPGDMDM2PTGER4PTGER2 | |
| SCHEMBL20795952 | 0.73 | MAPT (0.39) | BCHELIPENPC1RAB9AALDH1A1 | |
| SCHEMBL18839551 | 0.72 | PLAU (0.49) | MAPK1SMN1; SMN2PLAUCYP2C9 | |
| SCHEMBL5195760 | 0.71 | CYP3A4 (0.46) | PLAUCYP3A4MDM2MEN1KMT2A | |
| SCHEMBL17293197 | 0.70 | CHRNB2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689366-B2 | Compounds for MALT1 degredation | CORNELL UNIVERSITY (US) | 2020-06-23 | — | — | US | disclosed |
| EP-3535254-A1 | COMPOUNDS FOR MALT1 DEGRADATION | Cornell University Cornell Center For Technology, Enterprise & Commercialization ("CCTEC") (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20190263785-A1 | COMPOUNDS FOR MALT1 DEGRADATION | CORNELL UNIVERSITY (US) | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689366-B2 | Compounds for MALT1 degredation | CRBN, NFKB2, NFKB1 | BCHE 3446/4885LIPE 3805/4885NPC1 1096/4885 |
| US-20190263785-A1 | COMPOUNDS FOR MALT1 DEGRADATION | CRBN, NFKB2, NFKB1 | BCHE 3680/4885LIPE 3983/4885NPC1 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.