SCHEMBL21295623

SCHEMBL21295623

[c]1cccc2occ(-c3ccccc3)c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 2/20 0.38
ALDH1A1 P00352 7/20 0.37
SMN1; SMN2 Q16637 6/20 0.37
NPC1 O15118 5/20 0.37
KDM4E B2RXH2 5/20 0.37
RAB9A P51151 5/20 0.37
POLB P06746 3/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 5/20 0.36
TP53 P04637 3/20 0.36
CYP3A4 P08684 3/20 0.36
HPGD P15428 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HSD17B10 Q99714 2/20 0.36
ALOX15 P16050 2/20 0.36
ALOX12 P18054 2/20 0.36
USP2 O75604 1/20 0.36
BRCA1 P38398 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295629 0.84 ACVR1 (0.42) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL21295840 0.80 CYP2A6 (0.41) ALDH1A1SMN1; SMN2KDM4EMAPTTP53
SCHEMBL4076820 0.80 ATM (0.33) ACVR1
SCHEMBL21295958 0.75 KDM4E (0.39) ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A
SCHEMBL21295858 0.73 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2NPC1KDM4ERAB9A
SCHEMBL21297627 0.72 DPP4 (0.35) ALDH1A1KDM4ERAB9AHPGDMEN1
SCHEMBL496098 0.71
SCHEMBL3483028 0.70 MAOB (0.47) KDM4EMAOB
SCHEMBL21295696 0.70 PIN1 (0.41) PIN1ALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL1310425 0.70 PIN1 (0.56) PIN1ALDH1A1SMN1; SMN2NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed