SCHEMBL21295840

SCHEMBL21295840

[c]1cccc2occ(-c3cccnc3)c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 14/20 0.41
CYP3A4 P08684 7/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 3/20 0.41
TDO2 P48775 1/20 0.40
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP2C9 P11712 6/20 0.36
CYP2B6 P20813 6/20 0.36
CYP2C19 P33261 6/20 0.36
CYP2E1 P05181 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076820 0.84 ATM (0.33) CYP2A6
SCHEMBL21295629 0.83 ACVR1 (0.42) ALDH1A1HSD17B10LMNAMAPTHTT
SCHEMBL21295623 0.80 PIN1 (0.38) CYP3A4ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL21295661 0.76 PSMD14 (0.44) CYP2A6CYP3A4ALDH1A1CYP1A2TDO2
SCHEMBL21295774 0.74 PRKDC (0.44) CYP2A6CYP3A4ALDH1A1CYP1A2TDO2
SCHEMBL31730922 0.73 ACVR1 (0.49) CYP2A6CYP3A4ALDH1A1CYP1A2TDO2
SCHEMBL21295717 0.72 CYP2A6 (0.40) CYP2A6CYP3A4ALDH1A1CYP1A2TDO2
SCHEMBL21295958 0.71 KDM4E (0.39) ALDH1A1CYP1A2TDO2HSD17B10KDM4E
SCHEMBL23071560 0.70 CYP2A6 (0.50) CYP2A6CYP3A4ALDH1A1CYP1A2TDO2
SCHEMBL21295812 0.70 DYRK1A (0.45) CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed