SCHEMBL21295740

SCHEMBL21295740

[c]1cc2ccc(-c3ccncc3)cc2o1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.51
DYRK1A Q13627 2/20 0.46
AAK1 Q2M2I8 8/20 0.44
PDE3B Q13370 2/20 0.41
PDE3A Q14432 2/20 0.41
QDPR P09417 1/20 0.40
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
CLK1 P49759 1/20 0.38
PIK3CD O00329 2/20 0.36
PIK3CA P42336 2/20 0.36
PIK3CB P42338 2/20 0.36
PIK3CG P48736 2/20 0.36
MAP4K4 O95819 1/20 0.36
CDK8 P49336 1/20 0.36
CLK2 P49760 1/20 0.36
CDK7 P50613 1/20 0.36
CDK9 P50750 1/20 0.36
CDK5 Q00535 1/20 0.36
ACVR1 Q04771 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295901 0.86 DYRK1A (0.54) CYP19A1DYRK1AAAK1PDE3BPDE3A
SCHEMBL21295962 0.80 CYP19A1 (0.56) CYP19A1PIK3CDPIK3CAPIP5K1CPI4KA
SCHEMBL21295653 0.73 KDM4E (0.41) LMNAMAPTPIK3CDPIK3CAPIK3CG
SCHEMBL23924863 0.72 LMNA (0.55) CYP19A1DYRK1AAAK1QDPRLMNA
SCHEMBL9612000 0.71 LMNA (0.61) CYP19A1DYRK1AAAK1QDPRLMNA
SCHEMBL17123368 0.69 LMNA (0.58) CYP19A1DYRK1AAAK1QDPRLMNA
SCHEMBL17870639 0.67 CA12 (0.44) LMNAMAPT
SCHEMBL31700815 0.67 MAPK9 (0.58) CYP19A1DYRK1AQDPRLMNAMAPT
SCHEMBL21295857 0.67 CYP11B2 (0.54) CYP19A1
SCHEMBL693553 0.67 PGR (0.47) DYRK1AMAPTCLK1CLK2CDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed