SCHEMBL21295820

SCHEMBL21295820

Cc1cnccc1-c1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.42
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CYP19A1 P11511 1/20 0.38
PDE2A O00408 1/20 0.38
PDE10A Q9Y233 1/20 0.38
TRPA1 O75762 1/20 0.38
CCNC P24863 2/20 0.35
CDK8 P49336 2/20 0.35
SIRT3 Q9NTG7 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BUB1 O43683 1/20 0.33
CYP1A2 P05177 6/20 0.33
CYP17A1 P05093 5/20 0.33
LATS1 O95835 2/20 0.33
LATS2 Q9NRM7 1/20 0.33
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
METAP2 P50579 1/20 0.32
CDC25B P30305 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570279 0.86 MAOA (0.40) MAOAMAOBPDE10ACYP1A2CYP17A1
SCHEMBL9276374 0.79 MAOA (0.40) MAOAMAOBCCNCCDK8BUB1
SCHEMBL14840963 0.79 MAOA (0.40) MAOAMAOBBUB1CYP1A2METAP2
SCHEMBL28586625 0.77 RPS6KA3 (0.46) MAOAMAOBCYP1A2CYP17A1
SCHEMBL28917964 0.77 RPS6KA3 (0.46) MAOAMAOBCYP1A2CYP17A1
SCHEMBL981109 0.77 TSHR (0.39) TDP1CYP1A2METAP2
SCHEMBL28596660 0.76 GRM4 (0.36) GRM4CYP19A1CCNCCDK8CYP1A2
SCHEMBL28608524 0.76 CYP1A2 (0.31) TRPA1CYP1A2
SCHEMBL18421651 0.75 NCOA3 (0.40) MAOAMAOBCYP19A1PDE10ACYP1A2
SCHEMBL3304165 0.75 CYP1A2 (0.43) MAOAMAOBTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed