SCHEMBL28586625

SCHEMBL28586625

[c]1ccccc1-c1ccncc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KA3 P51812 3/20 0.46
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
CYP1A2 P05177 6/20 0.42
CYP2E1 P05181 3/20 0.42
CYP3A4 P08684 3/20 0.42
CYP2C8 P10632 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP2A6 P11509 3/20 0.42
CYP2C9 P11712 3/20 0.42
CYP2B6 P20813 3/20 0.42
CYP2C19 P33261 3/20 0.42
TNF P01375 1/20 0.41
CYP46A1 Q9Y6A2 1/20 0.40
LIMK1 P53667 1/20 0.38
FGFR1 P11362 2/20 0.38
SRC P12931 1/20 0.38
FGFR2 P21802 1/20 0.38
FGFR4 P22455 1/20 0.38
FGFR3 P22607 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28917964 0.93 RPS6KA3 (0.46) RPS6KA3MAOAMAOBCYP1A2CYP2E1
SCHEMBL9958209 0.80 NOTUM (0.41) RPS6KA3MAOAMAOBTNFFGFR1
SCHEMBL9958153 0.79 CYP2A6 (0.47) CYP1A2CYP2E1CYP3A4CYP2D6CYP2A6
SCHEMBL769410 0.79 ALDH1A1 (0.39) CYP2A6
SCHEMBL21692148 0.79 RPS6KA3 (0.59) RPS6KA3MAOAMAOBCYP1A2CYP2E1
SCHEMBL8716812 0.79 RPS6KA3 (0.65) RPS6KA3MAOAMAOBCYP1A2CYP2E1
SCHEMBL28586211 0.79 RPS6KA3 (0.33) RPS6KA3CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL2448843 0.77 ALDH1A1 (0.38) CYP2A6
SCHEMBL21295820 0.77 GRM4 (0.42) MAOAMAOBCYP1A2CYP17A1
SCHEMBL28570279 0.77 MAOA (0.40) MAOAMAOBCYP1A2CYP2E1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed