SCHEMBL981109

SCHEMBL981109

Cc1ccccc1-c1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ACHE P22303 2/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 4/20 0.35
PKM P14618 1/20 0.35
NOTUM Q6P988 1/20 0.35
GAA P10253 1/20 0.34
IDO1 P14902 1/20 0.34
METAP2 P50579 1/20 0.34
HPGD P15428 3/20 0.33
NISCH Q9Y2I1 1/20 0.33
DCUN1D1 Q96GG9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714181 0.88 TSHR (0.41) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL982199 0.87 TRPA1 (0.37) TSHRACHENPC1RAB9ASMN1; SMN2
SCHEMBL2761711 0.83 MEN1 (0.32) NPC1RAB9ASMN1; SMN2ALDH1A1MEN1
SCHEMBL322239 0.80 MEN1 (0.35) TSHRNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL8855149 0.80 MEN1 (0.35) TSHRNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL5325193 0.79 ELANE (0.38) SMN1; SMN2CYP3A4TDP1ALDH1A1GAA
SCHEMBL2458589 0.79 ELANE (0.38) NPC1RAB9ASMN1; SMN2CYP3A4TDP1
SCHEMBL3223109 0.77 CYP1A2 (0.40) TSHRACHECYP3A4TDP1ALDH1A1
SCHEMBL12816261 0.77 CYP1A2 (0.33) TSHRCYP1A2
SCHEMBL3912578 0.77 NPC1 (0.35) TSHRACHENPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-04-04 US claimed
EP-4270508-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP claimed
US-20230232700-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-07-20 US claimed
US-20230165124-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-05-25 US claimed
US-11581487-B2 Patterned conductive coating for surface of an opto-electronic device OTI LUMIONICS INC. (CA) 2023-02-14 US claimed
CN-110746369-B Method for synthesizing 4-amido isoxazole 华南理工大学 2022-06-14 CN claimed
CN-110746369-A Method for synthesizing 4-acylamino isoxazole 华南理工大学 2020-02-04 CN claimed
EP-2504324-B1 SULTAM DERIVATIVES HOFFMANN LA ROCHE (CH) 2015-02-25 EP claimed
US-8314250-B2 Sultam derivatives HOFFMANN-LA ROCHE INC. (US) 2012-11-20 US claimed
EP-2504324-A1 SULTAM DERIVATIVES F. Hoffmann-La Roche AG (CH) 2012-10-03 EP claimed
EP-1978967-B1 QUINAZOLINONE DERIVATIVES AS VANILLOID ANTAGONISTS NOVARTIS AG (CH) 2010-09-22 EP claimed
WO-2007135529-A2 AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS PFIZER PRODUCTS INC. (US) 2007-11-29 WO claimed
WO-2007135527-A2 BENZIMIDAZOLYL COMPOUNDS PFIZER PRODUCTS INC. (US) 2007-11-29 WO claimed
EP-1091930-B1 C-TERMINAL MODIFIED OXAMYL DIPEPTIDES AS INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES IDUN PHARMACEUTICALS INC (US) 2006-12-13 EP claimed
US-7053056-B2 C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases IDUN PHARMACEUTICALS, INC. (US) 2006-05-30 US claimed
US-6544951-B2 Antiinflammatory agents; autoimmune diseases, nervous system degradation IDUN PHARMACEUTICALS, INC. 2003-04-08 US claimed
US-6521667-B1 Calcilytic compounds NPS PHARMACEUTICALS, INC. 2003-02-18 US claimed
EP-0798291-B1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO LTD (JP) 2002-09-11 EP claimed
US-5968980-A ENDOPEPTIDASE 24.11 INHIBITORS SANTEN PHARMACEUTICAL CO., LTD. (JP) 1999-10-19 US claimed
EP-0798291-A1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 1997-10-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYBA TSHR 4436/4885ACHE 354/4885NPC1 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.