SCHEMBL21295880

SCHEMBL21295880

[c]1ccc(-c2ccccc2)c2sccc12

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.36
PDPK1 O15530 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2E1 P05181 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2B6 P20813 1/20 0.32
PTGS2 P35354 1/20 0.32
MAPT P10636 1/20 0.32
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295814 0.82 MAPK14 (0.39) ALDH1A1MAPT
SCHEMBL21295704 0.75 ADORA1 (0.42) ALDH1A1MAPK1MAPT
SCHEMBL7465123 0.72 ALDH1A1 (0.39) BCAT2ALDH1A1MAPK1CYP2A6CYP2B6
SCHEMBL21295846 0.70 BCAT2 (0.40) BCAT2PDPK1ALDH1A1CYP2E1CYP2A6
SCHEMBL8780074 0.70
SCHEMBL4805844 0.70 NPC1 (0.30)
SCHEMBL533267 0.68 PARP1 (0.35) ALDH1A1MAPK1CYP2A6MAPTBACE1
SCHEMBL19756685 0.67 ATR (0.46) BCAT2PDPK1ALDH1A1MAPK1CYP2A6
SCHEMBL21295867 0.67 MAPT (0.35) PDPK1CYP2E1CYP2A6CYP2B6MAPT
SCHEMBL2452059 0.65 ALDH1A1 (0.36) ALDH1A1MAPK1CYP2A6MAPTBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed