SCHEMBL21295867

SCHEMBL21295867

[c]1ccc2ccsc2c1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
CYP2A6 P11509 2/20 0.34
PDPK1 O15530 1/20 0.33
CYP2E1 P05181 1/20 0.32
CYP2B6 P20813 1/20 0.32
ADORA3 P0DMS8 1/20 0.31
ADORA1 P30542 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
ATR Q13535 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295881 0.82 MAPK14 (0.36) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL21296168 0.80 CYP2A6 (0.45) MAPTCYP2A6CYP2E1CYP2B6PDE4A
SCHEMBL21295729 0.75 ADORA1 (0.42) MAPTADORA1ADORA2A
SCHEMBL134135 0.68 ALDH1A1 (0.40) MAPTCYP2A6
SCHEMBL4311450 0.68 CYP2A6 (0.34) CYP2A6
SCHEMBL4306892 0.68 CYP2A6 (0.34) CYP2A6
SCHEMBL21295781 0.68 GPR3 (0.43) MAPT
SCHEMBL4580879 0.67 ALDH1A1 (0.47) MAPTCYP2A6CYP2E1CYP2B6
SCHEMBL19756685 0.67 ATR (0.46) MAPTCYP2A6PDPK1ATR
SCHEMBL21295880 0.67 BCAT2 (0.36) MAPTCYP2A6PDPK1CYP2E1CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed