SCHEMBL21295906

SCHEMBL21295906

[c]1cccc2sc3c(-c4ccncc4)cccc3c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 3/20 0.39
ALOX5 P09917 1/20 0.37
PDE10A Q9Y233 3/20 0.36
PIK3CD O00329 1/20 0.35
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33
IMPDH2 P12268 2/20 0.33
LIMK1 P53667 1/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
BACE1 P56817 1/20 0.32
BACE2 Q9Y5Z0 1/20 0.32
GSK3B P49841 2/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21297031 0.87 ALOX5 (0.42) TDO2ALOX5CYP17A1CYP1A2LIMK1
SCHEMBL28570827 0.79 KDM4E (0.34) TDO2PIK3CDCYP1A2LIMK1KDM4E
SCHEMBL20441890 0.79 ALOX5 (0.56) TDO2ALOX5PDE10APIK3CDCYP17A1
SCHEMBL21295649 0.78 RAB9A (0.36) TDO2ALOX5PDE10ACYP17A1CYP1A2
SCHEMBL21295913 0.78 KRAS (0.41) TDO2ALOX5PDE10ACYP1A2KDM4E
SCHEMBL21295845 0.74 ALOX5 (0.40) TDO2ALOX5PDE10APIK3CDCYP17A1
SCHEMBL21296094 0.74 ALOX5 (0.40) TDO2ALOX5PDE10APIK3CDCYP17A1
SCHEMBL21295885 0.72 LIMK1 (0.43) PIK3CDIMPDH2LIMK1KDM4ENPC1
SCHEMBL21295954 0.72 PIK3CA (0.40) PIK3CDLIMK1KDM4ENPC1RAB9A
SCHEMBL21295804 0.72 RAB9A (0.38) PIK3CDIMPDH2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed